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Showing 1–6 of 6 results

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Accommodation of vascularized xenografts: Expression of “protective genes” by donor endothelial cells in a host Th2 cytokine environment

Fritz H. Bach
Christiane Ferran
Waune W. Hancock
Research01 Feb 1997
Nature Medicine

Volume: 3, P: 196-204
Pasteurisation temperatures effectively inactivate influenza A viruses in milk

In response to the emergence of H5N1 influenza A viruses as a novel pathogen of cattle, this study shows that pasteurisation of cows’ milk should effectively inactivate the virus, but that it remains infectious in unpasteurised milk.

Jenna Schafers
Caroline J. Warren
Edward Hutchinson
ResearchOpen Access30 Jan 2025
Nature Communications

Volume: 16, P: 1-9
BTN3A3 evasion promotes the zoonotic potential of influenza A viruses

A protein that evolved in primates, BTN3A3, is expressed in human airways and shows antiviral activity against avian IAVs but not against human IAVs.

Rute Maria Pinto
Siddharth Bakshi
Massimo Palmarini
Research28 Jun 2023
Nature

Volume: 619, P: 338-347
Genome-wide CRISPR screen identifies host dependency factors for influenza A virus infection

Here, Li et al. perform a genome-wide CRISPR screen to identify host dependency factors for influenza A virus infection and show that the host mRNA cap methyltransferase CMTR1 is important for viral cap snatching and that it affects expression of antiviral genes.

Bo Li
Sara M. Clohisey
Nir Hacohen
ResearchOpen Access09 Jan 2020
Nature Communications

Volume: 11, P: 1-18
IFITM3 restricts the morbidity and mortality associated with influenza

Interferon-inducible transmembrane (IFITM) protein 3 is shown to be an innate defence mechanism against viral infection in vivo; furthermore, a subset of the patients hospitalized during the H1N1 2009 pandemic carried a variant form of the IFITM3 gene.

Aaron R. Everitt
Simon Clare
Paul Kellam
Research25 Mar 2012
Nature

Volume: 484, P: 519-523
PA-X antagonises MAVS-dependent accumulation of early type I interferon messenger RNAs during influenza A virus infection

Rachel E. Rigby
Helen M. Wise
Jan Rehwinkel
ResearchOpen Access10 May 2019
Scientific Reports

Volume: 9, P: 1-13