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Advanced filters: Author: Paul J. Cheng-Hathaway Clear advanced filters

Active PSF shaping and adaptive optics enable volumetric localization microscopy through brain sections

Active PSF shaping and adaptive optics are combined to enable 3D localization microscopy throughout thick tissues. The method was used to study the nanoscale architecture of amyloid fibrils in a mouse model of Alzheimer’s disease.

Michael J. Mlodzianoski
Paul J. Cheng-Hathaway
Fang Huang
Research16 Jul 2018
Nature Methods

Volume: 15, P: 583-586

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