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Showing 1–2 of 2 results
Advanced filters: Author: Paul M. Riegelhaupt Clear advanced filters

  • Tandem pore (K2P) potassium channels set the cellular resting membrane potential in tissues throughout the body. Here, authors show how the composition of phospholipid within the bilayer may directly alter gating in this family of ion channels.

    • Philipp A. M. Schmidpeter
    • John T. Petroff II
    • Paul M. Riegelhaupt
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-14

  • Schmidpeter and colleagues showed that anionic lipids bind to pacemaker ion channels and increase their activity by acting like keys that unlock salt bridges at the channel gates.

    • Philipp A. M. Schmidpeter
    • Di Wu
    • Crina M. Nimigean
    Research
    Nature Structural & Molecular Biology
    Volume: 29, P: 1092-1100