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Advanced filters: Author: Paulien E. Polderman Clear advanced filters

Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

Geert J. P. L. Kops
Tobias B. Dansen
Boudewijn M. T. Burgering
Research19 Sept 2002
Nature

Volume: 419, P: 316-321
Mitochondrial H₂O₂ release does not directly cause damage to chromosomal DNA

Nuclear DNA damage downstream of mitochondrial ROS is often cited to contribute to cancer initiation and aging. However, here the authors show that although H₂O₂ induces DNA mutations when produced near DNA, it does not when released by mitochondria.

Daan M. K. van Soest
Paulien E. Polderman
Tobias B. Dansen
ResearchOpen Access28 Mar 2024
Nature Communications

Volume: 15, P: 1-16

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Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress

Mitochondrial H2O2 release does not directly cause damage to chromosomal DNA

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Mitochondrial H₂O₂ release does not directly cause damage to chromosomal DNA