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Showing 1–7 of 7 results
Advanced filters: Author: Paulo Gustavo Kotze Clear advanced filters

  • An analysis of data from 522 population-based studies encompassing 82 global regions and spanning more than a century (1920–2024) shows spatiotemporal transitions across epidemiologic stages 1 to 3 of inflammatory bowel disease, and models stage 4 progression.

    • Lindsay Hracs
    • Joseph W. Windsor
    • Gilaad G. Kaplan
    ResearchOpen Access
    Nature
    Volume: 642, P: 458-466

  • Important studies published in 2023 outlined new agents and strategies for the management of inflammatory bowel disease. Therapeutic ambitions for the management of inflammatory bowel disease were raised by the success of combinations of biologic agents in ulcerative colitis and early surgical resection in Crohn’s disease.

    • Paulo Gustavo Kotze
    • Severine Vermeire
    News & Views
    Nature Reviews Gastroenterology & Hepatology
    Volume: 21, P: 84-85

  • Therapeutic drug monitoring (TDM) has been suggested as a useful tool for managing patients with inflammatory bowel disease on biologic therapy. This Perspective examines evidence and guidelines related to TDM in inflammatory bowel disease management and also strategies to optimize biologic treatment where TDM is not available.

    • Marjorie Argollo
    • Paulo Gustavo Kotze
    • Geert D’Haens
    Reviews
    Nature Reviews Gastroenterology & Hepatology
    Volume: 17, P: 702-710

  • Crohn’s disease is a progressive, destructive inflammatory bowel disease of unclear cause and involves chronic inflammation of any part of the gastrointestinal tract. This Primer reviews the epidemiology, pathophysiology, diagnosis and management of this disease.

    • Giulia Roda
    • Siew Chien Ng
    • Silvio Danese
    Reviews
    Nature Reviews Disease Primers
    Volume: 6, P: 1-19