G-quadruplexes (G4) DNA are DNA structures found throughout the genome previously shown to be bound with high specificity by the RecQ family helicase BLM. Here the authors describe how BLM interacts with G4 DNA in molecular details and propose an integrated model of the cooperative binding between BLM and G4 structures.
- Sujoy Chatterjee
- Jennifer Zagelbaum
- Eli Rothenberg
