Constipation is a common functional gastrointestinal disorder in children, characterized by withholding of stools, infrequent and painful passage of hard stools, and episodes of fecal incontinence. In this Review, the authors describe the prevalence and pathophysiology of childhood constipation as well as discuss the latest available knowledge on the diagnosis, treatment and follow-up of these pediatric patients.
- Suzanne M. Mugie
- Carlo Di Lorenzo
- Marc A. Benninga