Proteins linked to neurodegenerative diseases can potentially be used as biomarkers. A study now shows that after accounting for confounding variables such as age and blood contamination, cerebrospinal fluid levels of α-synuclein and DJ1 are substantially reduced in patients with Parkinson disease compared with healthy controls or individuals with Alzheimer disease.
- Penelope Foulds
- David M. A. Mann
- David Allsop