MicroRNAs (miRNAs) regulate the differentiation of adipoctyes, as well as endocrine and inflammatory processes in adipose tissues. In this Review, Arner and Kulyté addressed the characterization and functions of miRNA regulatory networks in human adipose tissue, in particular the networks that contribute to chronic low-level inflammation. The potential for targeting these networks, as well as individual miRNAs, in obesity and other metabolic disorders is also discussed.
