The Drosophila fs(1)K10 transcript is localized asymmetrically during oogenesis through a cis-acting RNA element called the TLS. The tertiary structure of this hairpin is now presented, and while it contains W-C base pairs, the RNA helix takes on an A' form conformation that is needed for correct subcellular targeting.
- Simon L Bullock
- Inbal Ringel
- Peter J Lukavsky
