New diagnostic strategies are needed to distinguish rarely arising urachal adenocarcinomas (UrC) from other types of adenocarcinomas, as therapy regimes differ. In situ metabolic differences between UrC and colorectal adenocarcinomas were revealed using mass spectrometry imaging combined with digital pathology. A classification accuracy of 87% was achieved, exceeding currently available approaches.
- Judith Martha Neumann
- Karsten Niehaus
- Henning Reis
