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Advanced filters: Author: Philip A. Cistrone Clear advanced filters

  • GLP-1 is a gut hormone with glucose-lowering activity. Here the authors report the peptide, P5, a variant of the GLP-1 receptor agonist exendin-4, with 'biased' signalling activity, and show that P5 improves glucose homeostasis in diabetic mice by increasing adipose tissue hyperplasia.

    • Hongkai Zhang
    • Emmanuel Sturchler
    • Richard A. Lerner
    ResearchOpen Access
    Nature Communications
    Volume: 6, P: 1-13