Nature Search

Intrauterine Hypoxia-Ischemia Increases N-Methyl-D-Aspartate-Induced cGMP Formation and Glutamate Accumulation in Cultured Rat Cerebellar Granule Cells

Zhengwei Cai
Ted Sigrest
Philip G Rhodes
Research01 Jul 1995
Pediatric Research

Volume: 38, P: 107-112
Tracking neurons across days with high-density probes

UnitMatch tracks neurons in electrophysiological recordings across multiple recording sessions. UnitMatch relies on the spike waveform and allows tracking neurons even when their functional properties change such as during memory formation.

Enny H. van Beest
Célian Bimbard
Matteo Carandini
ResearchOpen Access27 Sept 2024
Nature Methods

Volume: 22, P: 778-787
Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

Analyses of expression profiles from whole blood of 31,684 individuals identify cis-expression quantitative trait loci (eQTL) effects for 88% of genes and trans-eQTL effects for 37% of trait-associated variants.

Urmo Võsa
Annique Claringbould
Lude Franke
Research02 Sept 2021
Nature Genetics

Volume: 53, P: 1300-1310
ABNORMAL CEREBRAL ENERGY METABOLISM IN NEONATES WITH FOCAL SEIZURES

James Moorcraft
Nicholas M Bolas
George K Radda
Research01 Nov 1989
Pediatric Research

Volume: 26, P: 519
Common and distinct neural representations of aversive somatic and visceral stimulation in healthy individuals

Whether the brain processes different types of pain similarly or differently remains unknown. The authors show that an established neurologic pain signature responds to five different types of visceral and somatic pain; they also develop a new classifier that reliably discriminates between both pain modalities.

Lukas Van Oudenhove
Philip A. Kragel
Tor D. Wager
ResearchOpen Access23 Nov 2020
Nature Communications

Volume: 11, P: 1-11
Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour

This genome-wide study of age at first sexual intercourse and first birth identifies 371 signals driven by reproductive biology, externalising behaviour and environmental effects, with later onset associated with lower incidence of some diseases.

Melinda C. Mills
Felix C. Tropf
Felix R. Day
Research01 Jul 2021
Nature Human Behaviour

Volume: 5, P: 1717-1730
Short-Chain Acyl-Coenzyme A Dehydrogenase Deficiency in Mice

Philip A Wood
Brad A Amendt
Dawna Armstrong
Research01 Jan 1989
Pediatric Research

Volume: 25, P: 38-43
Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

Many genetic variants identified in genome-wide association studies are associated with gene expression. Here, Porcu et al. propose a transcriptome-wide summary statistics-based Mendelian randomization approach (TWMR) that, applied to 43 human traits, uncovers hundreds of previously unreported gene–trait associations.

Eleonora Porcu
Sina Rüeger
Zoltán Kutalik
ResearchOpen Access24 Jul 2019
Nature Communications

Volume: 10, P: 1-12
Choice-specific sequences in parietal cortex during a virtual-navigation decision task

The neural circuit dynamics in the mouse posterior parietal cortex are found to involve sequences of neural activation rather than longer-lived sustained neural activity states.

Christopher D. Harvey
Philip Coen
David W. Tank
Research14 Mar 2012
Nature

Volume: 484, P: 62-68
Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism

Moore and colleagues show that Mycobacterium tuberculosis induces miR-33 and miR-33* in macrophages to inhibit integrated pathways involved in autophagy, lysosomal function and fatty acid oxidation, and to support bacterial replication.

Mireille Ouimet
Stefan Koster
Kathryn J Moore
Research18 Apr 2016
Nature Immunology

Volume: 17, P: 677-686
OTTERS: a powerful TWAS framework leveraging summary-level reference data

Here, the authors present a TWAS framework OTTERS that adapts multiple polygenic risk score methods to estimate eQTL weights from summary-level eQTL data. Both simulation and real studies show OTTERS is powerful across a wide range of genetic architectures.

Qile Dai
Geyu Zhou
Jingjing Yang
ResearchOpen Access07 Mar 2023
Nature Communications

Volume: 14, P: 1-13
L. Joseph Butterfield, MD: A Man for All Seasons

Philip Sunshine
Comments & Opinion16 Nov 1999
Journal of Perinatology

Volume: 19, P: 176-178
Short-Chain Acyl-Coenzyme A Dehydrogenase Activity, Antigen, and Biosynthesis Are Absent in the BALB/cByJ Mouse

Brad A Amendt
Eric Freneaux
William J Rhead
Research01 Jun 1992
Pediatric Research

Volume: 31, P: 552-556
Book Reviews

Philip Oliver
Books & Arts01 Feb 1987
Heredity

Volume: 58, P: 156
Publisher Correction: Identification of 371 genetic variants for age at first sex and birth linked to externalising behavior

Melinda C. Mills
Felix C. Tropf
Felix R. Day
Amendments and Corrections28 Jul 2021
Nature Human Behaviour

Volume: 5, P: 1111
Dynamic sensory cues shape song structure in Drosophila

Drosophila male courtship songs were thought to have a fixed structure with song repetition variations introduced unintentionally because of neural noise; this behavioural assay and computational modelling study instead reveals that males use fast changes in sensory information to actively pattern individual song sequences.

Philip Coen
Jan Clemens
Mala Murthy
Research05 Mar 2014
Nature

Volume: 507, P: 233-237
Radiation-induced genomic instability and bystander effects: inter-related nontargeted effects of exposure to ionizing radiation

Sally A Lorimore
Philip J Coates
Eric G Wright
Reviews13 Oct 2003
Oncogene

Volume: 22, P: 7058-7069
Raloxifene Treatment Enhances Brain Activation during Recognition of Familiar Items: a Pharmacological fMRI Study in Healthy Elderly Males

Rutger Goekoop
Frederik Barkhof
Serge ARB Rombouts
Research16 Nov 2005
Neuropsychopharmacology

Volume: 31, P: 1508-1518

Search

Intrauterine Hypoxia-Ischemia Increases N-Methyl-D-Aspartate-Induced cGMP Formation and Glutamate Accumulation in Cultured Rat Cerebellar Granule Cells

Tracking neurons across days with high-density probes

Large-scale cis- and trans-eQTL analyses identify thousands of genetic loci and polygenic scores that regulate blood gene expression

ABNORMAL CEREBRAL ENERGY METABOLISM IN NEONATES WITH FOCAL SEIZURES

Common and distinct neural representations of aversive somatic and visceral stimulation in healthy individuals

Identification of 371 genetic variants for age at first sex and birth linked to externalising behaviour

Short-Chain Acyl-Coenzyme A Dehydrogenase Deficiency in Mice

Mendelian randomization integrating GWAS and eQTL data reveals genetic determinants of complex and clinical traits

Choice-specific sequences in parietal cortex during a virtual-navigation decision task

Mycobacterium tuberculosis induces the miR-33 locus to reprogram autophagy and host lipid metabolism

OTTERS: a powerful TWAS framework leveraging summary-level reference data

L. Joseph Butterfield, MD: A Man for All Seasons

Short-Chain Acyl-Coenzyme A Dehydrogenase Activity, Antigen, and Biosynthesis Are Absent in the BALB/cByJ Mouse

Book Reviews

Publisher Correction: Identification of 371 genetic variants for age at first sex and birth linked to externalising behavior

Dynamic sensory cues shape song structure in Drosophila

Radiation-induced genomic instability and bystander effects: inter-related nontargeted effects of exposure to ionizing radiation

Raloxifene Treatment Enhances Brain Activation during Recognition of Familiar Items: a Pharmacological fMRI Study in Healthy Elderly Males

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