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Showing 1–8 of 8 results
Advanced filters: Author: Philip G. Conaghan Clear advanced filters

  • This Perspective article discusses the stratification of patients with knee osteoarthritis (OA) in the context of current guidelines, biomarkers and emerging and future developments of targeted treatment. The authors aim to highlight how these novel developments can enhance the stratification of patients with knee OA to improve patient outcomes.

    • Nicholas R. Fuggle
    • Roland Chapurlat
    • Nicholas C. Harvey
    Reviews
    Nature Reviews Rheumatology
    Volume: 21, P: 684-695

  • 2012 has witnessed new developments in targeted therapies for osteoarthritis, and in ways to identify those patients who might benefit most from their application. Together, these advances could go some way to addressing the urgent need for disease-modifying treatments for this common disease.

    • Philip G. Conaghan
    News & Views
    Nature Reviews Rheumatology
    Volume: 9, P: 68-70

  • Traditionally, diagnosis of osteoarthritis has relied upon conventional radiography, but there are discrepancies between clinical symptoms and radiographic findings. Novel imaging modalities, especially MRI, are providing new insights into the osteoarthritis phenotype and the potential tissue origins of pain in joint disease.

    • Claire YJ Wenham
    • Philip G Conaghan
    Reviews
    Nature Reviews Rheumatology
    Volume: 5, P: 149-158

  • Current guidelines for the treatment of osteoarthritis involve exercise and lifestyle modifications as well as pharmaceutical therapeutics for effective pain management. Is this message reaching patients, and are they exercising enough?

    • Philip G. Conaghan
    News & Views
    Nature Reviews Rheumatology
    Volume: 14, P: 625-626

  • Pain management is presently the focus of osteoarthritis (OA) therapy, but traditional pain-relieving drugs such as NSAIDs and glucocorticoids have limited utility. In this Review, the next generation of OA analgesics and their potential mechanisms of action are discussed.

    • Philip G. Conaghan
    • Andrew D. Cook
    • Paul P. Tak
    Reviews
    Nature Reviews Rheumatology
    Volume: 15, P: 355-363

  • Osteoarthritis (OA) is the most common degenerative joint disorder. In this Primer, Pelletier and colleagues provide an update on the progress made in the field of OA epidemiology, pathophysiological mechanisms, diagnosis, prevention, disease management and quality of life.

    • Johanne Martel-Pelletier
    • Andrew J. Barr
    • Jean-Pierre Pelletier
    Reviews
    Nature Reviews Disease Primers
    Volume: 2, P: 1-18