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Advanced filters: Author: Philip Hanoian Clear advanced filters

  • Extrachromosomal DNA makes cancerous tumours resistant to treatment, but this research demonstrates that increasing transcription–replication conflict allows for targeted elimination of cancer cells containing extrachromosomal DNA, and thus sustained tumour regression in mice.

    • Jun Tang
    • Natasha E. Weiser
    • Howard Y. Chang
    ResearchOpen Access
    Nature
    Volume: 635, P: 210-218