Telogen lag is a delay period where the hair follicle is refractive to signals that stimulate regeneration. Even though this concept has been around for over 50 years, the molecular mechanisms behind this phenomenon are still poorly understood. This paper shows that bone morphogenetic proteins (BMPs) and their inhibitors are crucial molecules in controlling hair follicle waves and cycling.
- Maksim V. Plikus
- Julie Ann Mayer
- Cheng-Ming Chuong