Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–6 of 6 results
Advanced filters: Author: Philippe Nghe Clear advanced filters

  • The spontaneous emergence of autocatalytic RNAs is central to origin of life. Here, the authors use machine learning, high-throughput screening and statistical physics to explore large neutral space of catalytic RNAs.

    • Camille N. Lambert
    • Vaitea Opuu
    • Philippe Nghe
    ResearchOpen Access
    Nature Communications
    Volume: 16, P: 1-13

  • The coupling of autocatalysis to compartment growth and division is a key step in the origin of life. Now it has been shown that compartmentalizing the formose reaction in emulsion droplets leads to several crucial properties of living and evolving systems (growth, division, variation, competition, rudimentary heredity and selection).

    • Heng Lu
    • Alex Blokhuis
    • Andrew D. Griffiths
    Research
    Nature Chemistry
    Volume: 16, P: 70-78

  • Autocatalytic networks may have started evolution during the origin of life. Here, the authors establish a landscape of thousands of RNA networks by barcoded sequencing and microfluidics, and derive relationships between topology and Darwinian properties such as variation and differential reproduction.

    • Sandeep Ameta
    • Simon Arsène
    • Philippe Nghe
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-11

  • Sign epistasis clearly constrains evolution, but its causes are difficult to decipher. Here, the authors study epistasis in a signalling cascade, and arrive at a general criterion and understanding of sign epistasis as arising from the inherent hierarchy between signalling cascade components.

    • Philippe Nghe
    • Manjunatha Kogenaru
    • Sander J. Tans
    ResearchOpen Access
    Nature Communications
    Volume: 9, P: 1-9

  • The inherent stochasticity in metabolic reactions is a potent source of phenotypic heterogeneity in cell populations, with potentially fundamental implications for cancer research.

    • Daniel J. Kiviet
    • Philippe Nghe
    • Sander J. Tans
    Research
    Nature
    Volume: 514, P: 376-379