Nature Search

Neoadjuvant immune checkpoint blockade before chemoradiation for cervical squamous carcinoma (GINECO window-of-opportunity COLIBRI study): a phase II trial

Pre-treatment dual immune checkpoint blockade in cervical cancer remains understudied. In this trial, the authors show that neoadjuvant immune checkpoint blockade enhances immune activation and correlates with improved response to subsequent chemoradiation in patients with cervical carcinoma.

Isabelle Ray-Coquard
Marie-Christine Kaminsky-Forrett
Sarah Bétrian
ResearchOpen Access05 Jan 2026
Nature Communications

Volume: 17, P: 1-13
Population-wide cerebellar growth models of children and adolescents

The development of the human cerebellum is not well understood. Here, the authors analyse a large sample of neuroimaging scans from children and adolescents to develop growth models of the cerebellum which mirror age-related developmental trajectories of behaviour and function.

Carolin Gaiser
Rick van der Vliet
Ryan L. Muetzel
ResearchOpen Access18 Mar 2024
Nature Communications

Volume: 15, P: 1-15
Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus

A region on chromosome 19p13 is associated with the risk of developing ovarian and breast cancer. Here, the authors genotyped SNPs in this region in thousands of breast and ovarian cancer patients and identified SNPs associated with three genes, which were analysed with functional studies.

Kate Lawrenson
Siddhartha Kar
Simon A. Gayther
ResearchOpen Access07 Sept 2016
Nature Communications

Volume: 7, P: 1-22
Identification of BTG2, an antiproliferative p53–dependent component of the DNA damage cellular response pathway

Jean-Pierre Rouault
Nicole Falette
Alain Puisieux
Research01 Dec 1996
Nature Genetics

Volume: 14, P: 482-486
A novel thermochromic myocardial phantom for radiofrequency ablation and cryoablation

Carlo Saija
Sukruth Pradeep Kundur
Kawal Rhode
ResearchOpen Access07 Oct 2025
Scientific Reports

Volume: 15, P: 1-11
A comprehensive quantification of global nitrous oxide sources and sinks

Bottom-up and top-down approaches are used to quantify global nitrous oxide sources and sinks resulting from both natural and anthropogenic sources, revealing a 30% increase in global human-induced emissions between 1980 and 2016.

Hanqin Tian
Rongting Xu
Yuanzhi Yao
Research07 Oct 2020
Nature

Volume: 586, P: 248-256
Immunomic longitudinal profiling of the NeoPembrOv trial identifies drivers of immunoresistance in high-grade ovarian carcinoma

Changes in the tumour microenvironment have been associated with response and resistance to immunotherapy. Here, by performing longitudinal transcriptomic and spatial analysis, the authors report the exploratory analysis of their phase II trial of neoadjuvant chemotherapy alone or in combination with pembrolizumab (anti-PD1) in patients with advanced high-grade ovarian carcinoma.

Olivia Le Saux
Maude Ardin
Isabelle Ray-Coquard
ResearchOpen Access16 Jul 2024
Nature Communications

Volume: 15, P: 1-15
2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations

Nonsense mutations can be corrected by several molecules that activate readthrough of premature termination codon. Here, the authors report that 2,6-diaminopurine efficiently corrects UGA nonsense mutations with no significant toxicity.

Carole Trzaska
Séverine Amand
Fabrice Lejeune
ResearchOpen Access20 Mar 2020
Nature Communications

Volume: 11, P: 1-12
A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Breast cancer risk for BRCA1/BRCA2 mutation carriers varies depending on other genetic factors. Here, the authors perform a case-only genome-wide association study and highlight novel loci associated with breast cancer risk for BRCA1/BRCA2 mutation carriers.

Juliette Coignard
Michael Lush
Antonis C. Antoniou
ResearchOpen Access17 Feb 2021
Nature Communications

Volume: 12, P: 1-22
Confirmation of associations between ion channel gene SNPs and QTc interval duration in healthy subjects

L Gouas
V Nicaud
P Guicheney
Research30 May 2007
European Journal of Human Genetics

Volume: 15, P: 974-979
Cancer risk management strategies and perceptions of unaffected women 5 years after predictive genetic testing for BRCA1/2 mutations

Claire Julian-Reynier
Julien Mancini
Catherine Noguès
ResearchOpen Access26 Jan 2011
European Journal of Human Genetics

Volume: 19, P: 500-506
Time to prophylactic surgery in BRCA1/2 carriers depends on psychological and other characteristics

Claire Julian-Reynier
Anne-Déborah Bouhnik
Catherine Nogués
Research01 Oct 2010
Genetics in Medicine

Volume: 12, P: 801-807
Correction: Corrigendum: A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

Corine Bertolotto
Fabienne Lesueur
Brigitte Bressac-de Paillerets
Amendments and Corrections02 Dec 2015
Nature

Volume: 531, P: 126
Author Correction: Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus

Kate Lawrenson
Siddhartha Kar
Simon A. Gayther
Amendments and CorrectionsOpen Access08 Sept 2025
Nature Communications

Volume: 16, P: 1-2
A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

Corine Bertolotto
Fabienne Lesueur
Brigitte Bressac-de Paillerets
Research19 Oct 2011
Nature

Volume: 480, P: 94-98
Coactivation of nuclear receptors and myogenic factors induces the major BTG1 influence on muscle differentiation

Muriel Busson
Angel Carazo
Gérard Cabello
Research17 Jan 2005
Oncogene

Volume: 24, P: 1698-1710
Clinical relevance of 8q23, 15q13 and 18q21 SNP genotyping to evaluate colorectal cancer risk

Stéphanie Baert-Desurmont
Françoise Charbonnier
Thierry Frebourg
ResearchOpen Access15 Apr 2015
European Journal of Human Genetics

Volume: 24, P: 99-105
The normative modeling framework for computational psychiatry

This protocol guides the user through normative modeling analysis using the Predictive Clinical Neuroscience toolkit (PCNtoolkit), enabling individual differences to be mapped at the level of a single subject or observation in relation to a reference model.

Saige Rutherford
Seyed Mostafa Kia
Andre F. Marquand
Protocols01 Jun 2022
Nature Protocols

Volume: 17, P: 1711-1734
Cyclin-dependent kinase 1 expression is inhibited by p16^INK4a at the post-transcriptional level through the microRNA pathway

W W Chien
C Domenech
M Ffrench
Research20 Dec 2010
Oncogene

Volume: 30, P: 1880-1891
Ecological plasticity to ions concentration determines genetic response and dominance of Anopheles coluzzii larvae in urban coastal habitats of Central Africa

Neil M. Longo-Pendy
Billy Tene-Fossog
Diego Ayala
ResearchOpen Access04 Aug 2021
Scientific Reports

Volume: 11, P: 1-13
Isotopic systematics point to wild origin of mummified birds in Ancient Egypt

Marie Linglin
Romain Amiot
Christophe Lécuyer
ResearchOpen Access22 Sept 2020
Scientific Reports

Volume: 10, P: 1-12
Contribution of bioinformatics predictions and functional splicing assays to the interpretation of unclassified variants of the BRCA genes

Jean Christophe Théry
Sophie Krieger
Mario Tosi
Research15 Jun 2011
European Journal of Human Genetics

Volume: 19, P: 1052-1058
Mutation screening of MIR146A/B and BRCA1/2 3′-UTRs in the GENESIS study

Amandine I Garcia
Monique Buisson
Sylvie Mazoyer
Research20 Jan 2016
European Journal of Human Genetics

Volume: 24, P: 1324-1329
CAG repeat size in Huntingtin alleles is associated with cancer prognosis

Morgane Sonia Thion
Sophie Tézenas du Montcel
Sandrine Humbert
Research16 Mar 2016
European Journal of Human Genetics

Volume: 24, P: 1310-1315
Deep sexual dimorphism in adult medaka fish liver highlighted by multi-omic approach

Qin Qiao
Séverine Le Manach
Benjamin Marie
ResearchOpen Access26 Aug 2016
Scientific Reports

Volume: 6, P: 1-12
Asymmetry of parental origin in long QT syndrome: preferential maternal transmission of KCNQ1 variants linked to channel dysfunction

Hideki Itoh
Myriam Berthet
Pascale Guicheney
Research16 Dec 2015
European Journal of Human Genetics

Volume: 24, P: 1160-1166
Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Juliette Coignard
Michael Lush
Antonis C. Antoniou
Amendments and CorrectionsOpen Access14 May 2021
Nature Communications

Volume: 12, P: 1-2
AraDiv: a dataset of functional traits and leaf hyperspectral reflectance of Arabidopsis thaliana

Maria Stefania Przybylska
Cyrille Violle
François Vasseur
ResearchOpen Access24 May 2023
Scientific Data

Volume: 10, P: 1-8
Partial duplications of the MSH2 and MLH1 genes in hereditary nonpolyposis colorectal cancer

Stephanie Baert-Desurmont
Marie-Pierre Buisine
Thierry Frebourg
Research17 Jan 2007
European Journal of Human Genetics

Volume: 15, P: 383-386
Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations

David Tougeron
Emilie Fauquembergue
Jean-Baptiste Latouche
Research05 Jun 2009
Modern Pathology

Volume: 22, P: 1186-1195

Search

Neoadjuvant immune checkpoint blockade before chemoradiation for cervical squamous carcinoma (GINECO window-of-opportunity COLIBRI study): a phase II trial

Population-wide cerebellar growth models of children and adolescents

Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus

Identification of BTG2, an antiproliferative p53–dependent component of the DNA damage cellular response pathway

A novel thermochromic myocardial phantom for radiofrequency ablation and cryoablation

A comprehensive quantification of global nitrous oxide sources and sinks

Immunomic longitudinal profiling of the NeoPembrOv trial identifies drivers of immunoresistance in high-grade ovarian carcinoma

2,6-Diaminopurine as a highly potent corrector of UGA nonsense mutations

A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

Confirmation of associations between ion channel gene SNPs and QTc interval duration in healthy subjects

Cancer risk management strategies and perceptions of unaffected women 5 years after predictive genetic testing for BRCA1/2 mutations

Time to prophylactic surgery in BRCA1/2 carriers depends on psychological and other characteristics

Correction: Corrigendum: A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

Author Correction: Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus

A SUMOylation-defective MITF germline mutation predisposes to melanoma and renal carcinoma

Coactivation of nuclear receptors and myogenic factors induces the major BTG1 influence on muscle differentiation

Clinical relevance of 8q23, 15q13 and 18q21 SNP genotyping to evaluate colorectal cancer risk

The normative modeling framework for computational psychiatry

Cyclin-dependent kinase 1 expression is inhibited by p16^INK4a at the post-transcriptional level through the microRNA pathway

Ecological plasticity to ions concentration determines genetic response and dominance of Anopheles coluzzii larvae in urban coastal habitats of Central Africa

Isotopic systematics point to wild origin of mummified birds in Ancient Egypt

Contribution of bioinformatics predictions and functional splicing assays to the interpretation of unclassified variants of the BRCA genes

Mutation screening of MIR146A/B and BRCA1/2 3′-UTRs in the GENESIS study

CAG repeat size in Huntingtin alleles is associated with cancer prognosis

Deep sexual dimorphism in adult medaka fish liver highlighted by multi-omic approach

Asymmetry of parental origin in long QT syndrome: preferential maternal transmission of KCNQ1 variants linked to channel dysfunction

Author Correction: A case-only study to identify genetic modifiers of breast cancer risk for BRCA1/BRCA2 mutation carriers

AraDiv: a dataset of functional traits and leaf hyperspectral reflectance of Arabidopsis thaliana

Partial duplications of the MSH2 and MLH1 genes in hereditary nonpolyposis colorectal cancer

Tumor-infiltrating lymphocytes in colorectal cancers with microsatellite instability are correlated with the number and spectrum of frameshift mutations

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