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Showing 1–4 of 4 results
Advanced filters: Author: Pierre Stömmer Clear advanced filters

  • A synthetic nanocarrier based on DNA origami chassis offers control over valency, orientation and spatial arrangement of antibodies for simultaneously engaging immune signalling pathways, checkpoint inhibition and targeted co-stimulation in anticancer immunotherapy in vivo.

    • Klaus F. Wagenbauer
    • Nhi Pham
    • Hendrik Dietz
    ResearchOpen Access
    Nature Nanotechnology
    Volume: 18, P: 1319-1326

  • DNA origami can be used to control the movement of nanoscale assemblies. Here the authors construct multiple-micrometer-long hollow DNA filaments through which DNA pistons move with micrometer-per-second speeds.

    • Pierre Stömmer
    • Henrik Kiefer
    • Hendrik Dietz
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-10

  • Precision design of DNA origami needs precision validation. Here, the authors developed cryo-EM methods for obtaining high resolution structural data and for constructing pseudo-atomic models in a semi-automated fashion, allowing for iterative nanodevice inspection and refinement.

    • Massimo Kube
    • Fabian Kohler
    • Hendrik Dietz
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-10