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Showing 1–10 of 10 results
Advanced filters: Author: Piet P Geusens Clear advanced filters
  • High-resolution peripheral quantitative CT (HR pQCT) has emerged as a unique way to evaluate bone and joints, by producing high-resolution, 3D images of cortical and trabecular bonein vivo. In this Review, the authors describe how HR pQCT is used in the evaluation of bone and joint diseases, together with an evaluation of its technical features, advantages, limitations, and potential in basic research, clinical trials and clinical practice.

    • Piet Geusens
    • Roland Chapurlat
    • Joop van den Bergh
    Reviews
    Nature Reviews Rheumatology
    Volume: 10, P: 304-313
  • Study of the efficacy of fracture prevention approaches has been neglected in men, in comparison with women. Guidelines from the Endocrine Society for the management of osteoporosis and fracture risk in men are thus welcome, but further research into fracture prevention in men is required.

    • Piet P. M. Geusens
    • Joop P. van den Bergh
    News & Views
    Nature Reviews Rheumatology
    Volume: 8, P: 568-570
  • Periarticular bone erosions are a central feature of rheumatoid arthritis (RA) and their exact assessment is crucial for diagnosis, monitoring responses to therapy and aiding decision-making. High-resolution peripheral quantitative CT and MRI—two imaging modalities with the potential to improve the diagnosis and monitoring of RA—have now been compared.

    • Piet P. M. Geusens
    • Stephanie Finzel
    News & Views
    Nature Reviews Rheumatology
    Volume: 9, P: 385-386
  • The risk of experiencing a fracture is lower in men than in women beyond the age of 50 years, but the burden of fractures is, nevertheless, substantial in men. This difference in fracture incidence is likely to be accounted for by differences in bone-related and fall-related factors, which are outlined, along with other data relating to the epidemiology, pathophysiology and treatment options for osteoporosis in men, in this Review.

    • Piet Geusens
    • Philip Sambrook
    • Willem Lems
    Reviews
    Nature Reviews Rheumatology
    Volume: 5, P: 497-504
  • Several randomized controlled trials have investigated the effects of a number of drugs on the reduction of fracture risk in women with postmenopausal osteoporosis. Meanwhile, algorithms have become available to identify women at the highest risk of fractures. In this context, this article outlines patient- and drug-related determinants that contribute to the clinical decision about initiating and choosing drug therapy for the prevention of fractures.

    • Piet P Geusens
    • Christian H Roux
    • Marc C Hochberg
    Reviews
    Nature Clinical Practice Rheumatology
    Volume: 4, P: 240-248
  • Patients over the age of 50 years who present with a fracture seem to have the highest risk of subsequent fracture and also mortality immediately after the initial fracture is incurred. In this Review, the authors summarize the evidence that demonstrate this trend and discuss the factors that influence fracture risk. Finally, they propose a five-step systematic approach to management of patients who present with a fracture, aimed at preventing subsequent fracture, decreasing mortality rates and reducing undertreatment or overtreatment.

    • Joop P. van den Bergh
    • Tineke A. van Geel
    • Piet P. Geusens
    Reviews
    Nature Reviews Rheumatology
    Volume: 8, P: 163-172