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Showing 1–4 of 4 results
Advanced filters: Author: Pille Harrison Clear advanced filters

  • This is an issue edsumm for 32. Identification of the Palaeocene/Eocene thermal maximum in a marine sedimentary sequence shows that sea surface temperatures near the North Pole increased from roughly 18 degrees Celsius to over 23 degrees Celsius — such warm values imply the absence of ice and thus exclude the influence of ice-albedo feedbacks on this Arctic warming.

    • Wendy Thomson
    • Anne Barton
    • Jane Worthington
    Research
    Nature Genetics
    Volume: 39, P: 1431-1433

  • Jane Worthington and colleagues report that three SNPs, located on chromosomes 10p15, 12q13 and 22q13, are associated with susceptibility to rheumatoid arthritis. These SNPs had previously been putatively associated with rheumatoid arthritis in the genome-wide association study conducted by the Wellcome Trust Case Control Consortium.

    • Anne Barton
    • Wendy Thomson
    • Jane Worthington
    Research
    Nature Genetics
    Volume: 40, P: 1156-1159

  • Soumya Raychaudhuri and colleagues demonstrate the utility of GRAIL, a software program used to prioritize results from genome-wide association studies for further replication, applied here to rheumatoid arthritis. The authors seek replication of their predictions in additional independent cohorts and report three new genetic loci associated with RA susceptibility.

    • Soumya Raychaudhuri
    • Brian P Thomson
    • Robert M Plenge
    Research
    Nature Genetics
    Volume: 41, P: 1313-1318