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Advanced filters: Author: Pinou Lv Clear advanced filters

  • SynGAP and PSD-95 are two abundant proteins that form a complex and undergo liquid–liquid phase separation (LLPS) in the postsynaptic density of neurons. Now, O-GlcNAcylation of SynGAP has been found to suppress LLPS of the SynGAP/PSD-95 complex, and O-GlcNAc-dependent LLPS was also shown to be dynamically regulated by the enzymes O-GlcNAc transferase and O-GlcNAcase.

    • Pinou Lv
    • Yifei Du
    • Xing Chen
    Research
    Nature Chemistry
    Volume: 14, P: 831-840