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Showing 1–7 of 7 results

Advanced filters: Author: Prasad Phapale Clear advanced filters

msiFlow: automated workflows for reproducible and scalable multimodal mass spectrometry imaging and microscopy data analysis

This paper introduces msiFlow, an open-source software for scalable and reproducible end-to-end multimodal image analysis. Using msiFlow, the authors explore the molecular heterogeneity of leukocytes in infected tissues.

Philippa Spangenberg
Sebastian Bessler
Daniel R. Engel
ResearchOpen Access27 Jan 2025
Nature Communications

Volume: 16, P: 1-13
SpaceM reveals metabolic states of single cells

SpaceM combines light microscopy and MALDI-imaging mass spectrometry to enable single-cell metabolic profiling of cultured cells. SpaceM reveals coexisting metabolic states of hepatocytes and aims to democratize single-cell metabolomics.

Luca Rappez
Mira Stadler
Theodore Alexandrov
Research05 Jul 2021
Nature Methods

Volume: 18, P: 799-805
Bioaccumulation of therapeutic drugs by human gut bacteria

An analysis of the interactions between 15 drugs and 25 gut bacterial strains shows that bioaccumulation of drugs within bacterial cells is another mechanism through which gut microorganisms can alter drug availability and efficacy.

Martina Klünemann
Sergej Andrejev
Kiran R. Patil
Research08 Sept 2021
Nature

Volume: 597, P: 533-538
Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking

GNPS is an open-access community-curated analysis platform for sharing natural product mass spectrometry data that enables continuous, automatic reanalysis of deposited 'living' data sets.

Mingxun Wang
Jeremy J Carver
Nuno Bandeira
Reviews09 Aug 2016
Nature Biotechnology

Volume: 34, P: 828-837
FDR-controlled metabolite annotation for high-resolution imaging mass spectrometry

The authors present a computational framework for false-discovery-rate-controlled metabolite annotation from high-resolution imaging mass spectrometry data.

Andrew Palmer
Prasad Phapale
Theodore Alexandrov
Research14 Nov 2016
Nature Methods

Volume: 14, P: 57-60
The reproduction process of Gram-positive protocells

Dheeraj Kanaparthi
Marko Lampe
Tillmann Lueders
ResearchOpen Access25 Mar 2024
Scientific Reports

Volume: 14, P: 1-15
3D molecular cartography using LC–MS facilitated by Optimus and 'ili software

3D molecular cartography is used for mapping of metabolites in our environment. This protocol describes the procedures for sample collection and processing, mass spectrometry analysis, and data processing and visualization.

Ivan Protsyuk
Alexey V Melnik
Theodore Alexandrov
Protocols21 Dec 2017
Nature Protocols

Volume: 13, P: 134-154