Formulation of carboxymethyl cellulose (CMC) and chitosan (CHI) hydrogel containing curcumin-loaded microcapsules (Cur-M) are developed for intratumoral injection. The Cur-M-loaded CMC and CHI (CCH) formulation forms a Cur-M-loaded CCH depot after mixing via electrostatic interactions between the anionic CMC and cationic CHI. The Cur-M-loaded CCH depot lead to greater inhibition of tumor growth.
- Seung Hun Park
- Da Yeon Kim
- Moon Suk Kim
