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Showing 1–1 of 1 results
Advanced filters: Author: Praseuth Yang Clear advanced filters

  • Patients with spinocerebellar ataxia type 1 express ataxin-1 with an extended polyglutamine (polyQ) tract that forms distinctive nuclear bodies. Here, the authors characterize the cellular pathways affected by polyQ-ataxin-1, showing that it disrupts multiple nuclear transport processes.

    • Sunyuan Zhang
    • Nicholas A. Williamson
    • Marie A. Bogoyevitch
    ResearchOpen Access
    Nature Communications
    Volume: 11, P: 1-16