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Advanced filters: Author: Prashanthini Jeyarajan Clear advanced filters

  • Random mutagenesis can uncover novel genes involved in phenotypic traits. Here the authors perform a large-scale phenotypic screen on over 100 mouse strains generated by ENU mutagenesis to identify mice with age-related diseases, which they attribute to specific mutations revealed by whole-genome sequencing.

    • Paul K. Potter
    • Michael R. Bowl
    • Steve D. M. Brown
    ResearchOpen Access
    Nature Communications
    Volume: 7, P: 1-13