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Advanced filters: Author: Prem Singh Kaushal Clear advanced filters

Structure of a group II intron in complex with its reverse transcriptase

A 3.8-Å cryo-EM structure of a bacterial group IIA intron in complex with its intron-encoded protein reveals how the reverse transcriptase domain interacts with the mobile intron RNA as well as structural similarities with eukaryotic telomerase and spliceosomal components.

Guosheng Qu
Prem Singh Kaushal
Hong-Wei Wang
Research02 May 2016
Nature Structural & Molecular Biology

Volume: 23, P: 549-557
ResR/McdR-regulated protein translation machinery contributes to drug resilience in Mycobacterium tuberculosis

ResR/McdR regulates ribosomal activity and is pivotal for proliferation and crucial metabolic activities in Mycobacterium tuberculosis, thereby contributing to drug resilience in this pathogen.

Pramila Pal
Mohd Younus Khan
Nisheeth Agarwal
ResearchOpen Access11 Jul 2023
Communications Biology

Volume: 6, P: 1-16

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Structure of a group II intron in complex with its reverse transcriptase

ResR/McdR-regulated protein translation machinery contributes to drug resilience in Mycobacterium tuberculosis

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