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Showing 1–2 of 2 results
Advanced filters: Author: Priyatama Pandey Clear advanced filters

  • Down syndrome has a high co-morbidity with immune and hematopoietic disorders. Here, the authors perform an epigenome-wide association study in newborns with and without Down syndrome to find differential methylation across the genome, including in hematopoietic regulators RUNX1 and FLI1.

    • Ivo S. Muskens
    • Shaobo Li
    • Adam J. de Smith
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-15

  • Lysine acetylation regulates the function of soluble proteins in vivo, yet it remains largely unexplored whether lysine acetylation regulates the function of membrane proteins. Here, the authors map lysine acetylation predominantly in membrane-interaction regions in peripheral membrane proteins and show with three candidate proteins how lysine acetylation is a regulator of membrane protein function.

    • Alan K. Okada
    • Kazuki Teranishi
    • Ralf Langen
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-12