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Showing 1–6 of 6 results

Advanced filters: Author: Punit Saraon Clear advanced filters

Seminal plasma as a diagnostic fluid for male reproductive system disorders

Seminal plasma is a potential source of biomarkers of male reproductive system disorders. Drabovich et al. describe the development of seminal plasma proteomics and the progress towards the clinical use of biomarkers of male infertility and prostate cancer.

Andrei P. Drabovich
Punit Saraon
Eleftherios P. Diamandis
Reviews08 Apr 2014
Nature Reviews Urology

Volume: 11, P: 278-288
A drug discovery platform to identify compounds that inhibit EGFR triple mutants

A high-throughput small-molecule drug screening platform enabled the detection of compounds targeting the functional interactions of receptor tyrosine kinases and identifies four new EGFR triple-mutant inhibitors.

Punit Saraon
Jamie Snider
Igor Stagljar
Research24 Feb 2020
Nature Chemical Biology

Volume: 16, P: 577-586
OICR-41103 as a chemical probe for the DCAF1 WD40 domain

OICR-41103 is a potent, selective probe targeting the DCAF1 WDR domain and displacing viral Vpr protein. It enables new opportunities in cancer research, antiviral therapy, and targeted protein degradation via PROTACs.

Serah W. Kimani
Mahmoud Noureldin
Levon Halabelian
ResearchOpen Access19 Jul 2025
Communications Biology

Volume: 8, P: 1-12
Testing cancer inhibitors at scale

A scalable and fast method for profiling single-molecule protein–protein interactions predicts the sensitivity of cells to inhibitors of the epidermal growth factor receptor, which is typically overexpressed in cancer.

Punit Saraon
Ingrid Grozavu
Igor Stagljar
News & Views02 Apr 2018
Nature Biomedical Engineering

Volume: 2, P: 203-204
CDC40 suppression induces CDCA5 splicing defects and anti-proliferative effects in lung cancer cells

Die Hu
Brigitte L. Thériault
Rima Al-awar
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-15
Receptor tyrosine kinases and cancer: oncogenic mechanisms and therapeutic approaches

Punit Saraon
Shivanthy Pathmanathan
Igor Stagljar
Reviews02 Jun 2021
Oncogene

Volume: 40, P: 4079-4093