Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–6 of 6 results
Advanced filters: Author: Qianzhen Shao Clear advanced filters

  • Empirically observed regiochemistries indicate that the CF2H radical has a nucleophilic character similar to alkyl radicals, but the CF3 radical is electrophilic in reactions with heterocycles. Here, the authors report DFT calculations, reproducing experimental selectivities and leading to an explanation of this difference.

    • Meng Duan
    • Qianzhen Shao
    • K. N. Houk
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-9

  • Tetraarylmethanes display special properties due to their spherical nature and are applied in various areas, but strategies for their asymmetric production are lacking. Now, their enantioselective synthesis is reported and in vitro studies indicate their potential as anticancer agents.

    • Xingguang Li
    • Meng Duan
    • Jianwei Sun
    Research
    Nature Catalysis
    Volume: 3, P: 1010-1019

  • Tetrasubstituted olefins have been explored as chemical synthons and can sometime have useful photophysical properties, but are sometimes difficult to synthesize with high selectivity in mild conditions. Here the authors present a method to make tetrasubstituted olefins via dual photo- and nickel catalysis, without the need for an inert atmosphere.

    • Yantao Li
    • Qianzhen Shao
    • Jin Xie
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-8

  • This Perspective highlights the vital role of physics-based modeling in computational enzyme engineering, exploring key advances, challenges and future steps. By integrating machine learning, these approaches can enhance each other, unlocking the full potential of enzyme design and discovery.

    • Christopher Jurich
    • Qianzhen Shao
    • Zhongyue J. Yang
    Reviews
    Nature Computational Science
    Volume: 5, P: 279-291