Cryo-electron microscopy structures of three varicella-zoster virus (VZV) capsids show VZV-specific features of the capsid-associated tegument complex (CATC) and genome packaging. The authors conclude that the VZV capsid is less stable and the CATC binds more weakly than in the homologues in other herpesviruses, characteristics that are linked to the small genome size of VZV.
- Wei Wang
- Qingbing Zheng
- Ningshao Xia