Nature Search

Intranasal influenza-vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response in hamsters

Understanding the utility of SARS -CoV-2 vaccination platforms and strategies through the emerging pandemic and beyond are critical to understanding the efficacy of such interventions. Here the authors assess nasal delivery of an influenza virus based viral vector for vaccination against SARS-CoV-2 in a hamsters model and assess the induced immunity.

Liang Zhang
Yao Jiang
Ningshao Xia
ResearchOpen Access11 Jul 2023
Nature Communications

Volume: 14, P: 1-18
Intracerebral fate of organic and inorganic nanoparticles is dependent on microglial extracellular vesicle function

Nanoparticle clearance is critical for safety and therapeutic applicability. Here the authors report the modulatory role of microglial extracellular vesicles on the brain clearance of organic and inorganic nanoparticles and provide a strategy to control their intracerebral fate.

Jinchao Gao
Qingxiang Song
Xiaoling Gao
Research29 Dec 2023
Nature Nanotechnology

Volume: 19, P: 376-386
Intratumor graph neural network recovers hidden prognostic value of multi-biomarker spatial heterogeneity

Cancer prognosis using multiregion sampling is costly and not completely reliable due to the required biomarker homogenisation step. Here, the authors develop an intratumor graph neural network for prognosis in multiregion cancer samples based on in situ biomarkers and gene expression that does not need homogenisation.

Lida Qiu
Deyong Kang
Haohua Tu
ResearchOpen Access22 Jul 2022
Nature Communications

Volume: 13, P: 1-12
Selenide-catalyzed enantioselective synthesis of trifluoromethylthiolated tetrahydronaphthalenes by merging desymmetrization and trifluoromethylthiolation

Catalytic enantioselective synthesis of trifluoromethylthiolated molecules remains a challenge. Here, the authors report a bifunctional selenide-catalyzed approach for the synthesis of structurally complex chiral trifluoromethylthiolated tetrahydronaphthalenes by merging desymmetrization and trifluoromethylthiolation.

Jie Luo
Qingxiang Cao
Xiaodan Zhao
ResearchOpen Access06 Feb 2018
Nature Communications

Volume: 9, P: 1-9
Arginase 1 drives mitochondrial cristae remodeling and PANoptosis in ischemia/hypoxia-induced vascular dysfunction

Han She
Jie Zheng
Tao Li
ResearchOpen Access28 May 2025
Signal Transduction and Targeted Therapy

Volume: 10, P: 1-20
Subsidence prediction of overburden strata and ground surface in shallow coal seam mining

Jian Cao
Qingxiang Huang
Lingfei Guo
ResearchOpen Access23 Sept 2021
Scientific Reports

Volume: 11, P: 1-12
Influence of two kinds of clearance joints on the dynamics of planar mechanical system based on a modified contact force model

Haiyan Tan
Li Li
Donglin Yu
ResearchOpen Access23 Nov 2023
Scientific Reports

Volume: 13, P: 1-27
Evaluation of different mathematical models on fitting the in vitro gas production parameters in beef cattle

Jinze Wang
Zhiyu Zhou
Zhenming Zhou
ResearchOpen Access24 Feb 2025
Scientific Reports

Volume: 15, P: 1-16
TGF-βRII regulates glucose metabolism in oral cancer-associated fibroblasts via promoting PKM2 nuclear translocation

Fanglong Wu
Shimeng Wang
Hongmei Zhou
ResearchOpen Access10 Jan 2022
Cell Death Discovery

Volume: 8, P: 1-10
Estimating ruminal crude protein degradation from beef cattle feedstuff

Chang Liu
Deyong Li
Zhenming Zhou
ResearchOpen Access06 Aug 2019
Scientific Reports

Volume: 9, P: 1-8
Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro

Yaoxing Wu
Qingxiang Liu
Jun Cui
ResearchOpen Access21 Mar 2017
Cell Discovery

Volume: 3, P: 1-14
Erratum: Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro

Yaoxing Wu
Qingxiang Liu
Jun Cui
Amendments and CorrectionsOpen Access11 Apr 2017
Cell Discovery

Volume: 3, P: 1
Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer

Fanglong Wu
Jin Yang
Hongmei Zhou
ReviewsOpen Access10 Jun 2021
Signal Transduction and Targeted Therapy

Volume: 6, P: 1-35

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Intranasal influenza-vectored COVID-19 vaccine restrains the SARS-CoV-2 inflammatory response in hamsters

Intracerebral fate of organic and inorganic nanoparticles is dependent on microglial extracellular vesicle function

Intratumor graph neural network recovers hidden prognostic value of multi-biomarker spatial heterogeneity

Selenide-catalyzed enantioselective synthesis of trifluoromethylthiolated tetrahydronaphthalenes by merging desymmetrization and trifluoromethylthiolation

Arginase 1 drives mitochondrial cristae remodeling and PANoptosis in ischemia/hypoxia-induced vascular dysfunction

Subsidence prediction of overburden strata and ground surface in shallow coal seam mining

Influence of two kinds of clearance joints on the dynamics of planar mechanical system based on a modified contact force model

Evaluation of different mathematical models on fitting the in vitro gas production parameters in beef cattle

TGF-βRII regulates glucose metabolism in oral cancer-associated fibroblasts via promoting PKM2 nuclear translocation

Estimating ruminal crude protein degradation from beef cattle feedstuff

Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro

Erratum: Zika virus evades interferon-mediated antiviral response through the co-operation of multiple nonstructural proteins in vitro

Signaling pathways in cancer-associated fibroblasts and targeted therapy for cancer

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