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Showing 1–3 of 3 results
Advanced filters: Author: Quentin Verron Clear advanced filters

  • It remains challenging to characterise somatic copy number alterations (SCNAs) in tumors and the surrounding tissues with spatial and single-cell resolution. Here, the authors develop the scCUTseq approach to characterise SCNAs from single cells in multi-region prostate cancer samples and identify pseudo-diploid cells and subclones.

    • Ning Zhang
    • Luuk Harbers
    • Nicola Crosetto
    ResearchOpen Access
    Nature Communications
    Volume: 15, P: 1-17

  • γδ T cells are unique T lymphocytes with cytotoxic functions, targeting infections and tumours. Here authors show that the target killing function of γδ T cells is tightly regulated at the level of the availability of lytic molecules granzyme B and perforin.

    • Patrick A. Sandoz
    • Kyra Kuhnigk
    • Björn Önfelt
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-16