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Cell Death and Differentiation (1)

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Advanced filters: Author: R A Chaurio Clear advanced filters

IgA transcytosis and antigen recognition govern ovarian cancer immunity

In patients with high-grade serous ovarian cancer, robust and protective humoral responses are dominated by B-cell-derived polyclonal IgA that binds to polymeric IgA receptors that are universally expressed on ovarian cancer cells.

Subir Biswas
Gunjan Mandal
Jose R. Conejo-Garcia
ResearchOpen Access03 Feb 2021
Nature

Volume: 591, P: 464-470
IRE1α–XBP1 controls T cell function in ovarian cancer by regulating mitochondrial activity

In human and mouse models of ovarian cancer, endoplasmic reticulum stress and the activation of the IRE1α–XBP1 pathway decreases the metabolic fitness of T cells and limits their anti-tumour functions.

Minkyung Song
Tito A. Sandoval
Juan R. Cubillos-Ruiz
Research10 Oct 2018
Nature

Volume: 562, P: 423-428
A blast without power – cell death induced by the tuberculosis-necrotizing toxin fails to elicit adequate immune responses

C Maueröder
R A Chaurio
L E Munoz
Research04 Mar 2016
Cell Death & Differentiation

Volume: 23, P: 1016-1025