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Showing 51–100 of 150 results

Advanced filters: Author: R D Mittal Clear advanced filters

A vertebral skeletal stem cell lineage driving metastasis

Vertebral osteoblasts in mouse and human are formed from a precursor skeletal stem cell population that is distinct from long bone skeletal stem cells in function, location and transcriptional programme.

Jun Sun
Lingling Hu
Matthew B. Greenblatt
Research13 Sept 2023
Nature

Volume: 621, P: 602-609
PRSS2 remodels the tumor microenvironment via repression of Tsp1 to stimulate tumor growth and progression

Tsp-1 in the tumor microenvironment is known to suppress tumor growth and progression. Here the authors show that PRSS2 represses Tsp-1 by binding to lipoprotein receptor-related protein 1 and suggest targeting PRSS2 mediated Tsp-1 repression as a potential therapeutic strategy.

Lufei Sui
Suming Wang
Randolph S. Watnick
ResearchOpen Access27 Dec 2022
Nature Communications

Volume: 13, P: 1-19
Wireless, closed-loop, smart bandage with integrated sensors and stimulators for advanced wound care and accelerated healing

A wireless ‘smart’ bandage stimulates wound healing.

Yuanwen Jiang
Artem A. Trotsyuk
Zhenan Bao
Research24 Nov 2022
Nature Biotechnology

Volume: 41, P: 652-662
Increased face detection responses on the mooney faces test in people at clinical high risk for psychosis

Steven M. Silverstein
Judy L. Thompson
Philip R. Corlett
ResearchOpen Access17 May 2021
npj Schizophrenia

Volume: 7, P: 1-7
Epithelial-to-mesenchymal transition is not required for lung metastasis but contributes to chemoresistance

An epithelial-to-mesenchymal transition (EMT) lineage-tracing system in a mouse model of breast-to-lung metastasis reveals that although some cells undergo EMT in a primary epithelial tumour, the lung metastases mainly arise from cells that have not undergone EMT; in addition, cells that have undergone EMT appear more resistant to chemotherapy.

Kari R. Fischer
Anna Durrans
Dingcheng Gao
Research11 Nov 2015
Nature

Volume: 527, P: 472-476
Disrupting biological sensors of force promotes tissue regeneration in large organisms

Humans and other large mammals heal wounds by forming fibrotic scar tissue with diminished function. Here, the authors show that disrupting mechanotransduction through the focal adhesion kinase pathway in large animals accelerates healing, prevents fibrosis, and enhances skin regeneration.

Kellen Chen
Sun Hyung Kwon
Geoffrey C. Gurtner
ResearchOpen Access06 Sept 2021
Nature Communications

Volume: 12, P: 1-15
Copper depletion modulates mitochondrial oxidative phosphorylation to impair triple negative breast cancer metastasis

Copper depletion has been reported to improve survival in patients with triple negative breast cancer (TNBC) but the underlying mechanisms are not completely understood. Here, the authors show that copper chelation reduces mitochondrial oxidative phosphorylation leading to decreased TNBC metastasis.

Divya Ramchandani
Mirela Berisa
Vivek Mittal
ResearchOpen Access15 Dec 2021
Nature Communications

Volume: 12, P: 1-16
Pan-cancer study detects genetic risk variants and shared genetic basis in two large cohorts

Pleiotropic loci and genome-wide genetic correlations have identified shared heritability across some types of cancers. Here, the authors perform genome-wide association studies and characterize pan-cancer heritability and pleiotropy in individuals of European ancestry across 18 cancer types from two large cohorts.

Sara R. Rashkin
Rebecca E. Graff
John S. Witte
ResearchOpen Access04 Sept 2020
Nature Communications

Volume: 11, P: 1-14
Long-term outcomes of consecutive patients of oropharyngeal cancer treated with radical radiotherapy

Ashwini Budrukkar
Sheetal R. Kashid
Jai Prakash Agarwal
ResearchOpen Access29 Jul 2025
BJC Reports

Volume: 3, P: 1-8
A telomere-targeting drug depletes cancer initiating cells and promotes anti-tumor immunity in small cell lung cancer

Therapeutic options for small cell lung cancer (SCLC) are limited. Here the authors show that a telomere-targeting drug, 6-Thio-2’-deoxyguanosine, inhibits growth of SCLC tumors by inducing telomere dysfunction preferentially in cancer initiating cells and promoting anti-tumor immune responses.

Buse Eglenen-Polat
Ryan R. Kowash
Esra A. Akbay
ResearchOpen Access22 Jan 2024
Nature Communications

Volume: 15, P: 1-18
An integrated binary metaheuristic approach in dynamic unit commitment and economic emission dispatch for hybrid energy systems

S Syama
J Ramprabhakar
Josep M. Guerrero
ResearchOpen Access14 Oct 2024
Scientific Reports

Volume: 14, P: 1-37
Global 3′ UTR shortening has a limited effect on protein abundance in proliferating T cells

The use of alternative polyadenylation sites can potentially result in mRNA being more or less susceptible to interaction with modulators of translation or stability. Here Gruber et al. find that the shortening of 3′UTRs observed in proliferating T cells does not significantly impact protein abundance.

Andreas R. Gruber
Georges Martin
Mihaela Zavolan
Research21 Nov 2014
Nature Communications

Volume: 5, P: 1-10
Bio-inspired preparation of Ag NPs, rGO, and Ag/rGO nanocomposites for acoustical, antioxidant, and plant growth regulatory studies

Prashant D. Sarvalkar
Anuj S. Jagtap
Avinash A. Ramteke
ResearchOpen Access25 Jan 2025
Scientific Reports

Volume: 15, P: 1-13
A high-resolution protein architecture of the budding yeast genome

A ChIP–exo method is used to define the genome-wide positional organization of proteins associated with gene transcription, DNA replication, centromeres, subtelomeres and transposons, revealing distinct protein assemblies for constitutive and inducible gene expression.

Matthew J. Rossi
Prashant K. Kuntala
B. Franklin Pugh
Research10 Mar 2021
Nature

Volume: 592, P: 309-314
The electroencephalography protocol for the Accelerating Medicines Partnership® Schizophrenia Program: Reliability and stability of measures

Daniel H. Mathalon
Spero Nicholas
Gregory A. Light
ResearchOpen Access06 Jun 2025
Schizophrenia

Volume: 11, P: 1-18
Obesity alters the lung myeloid cell landscape to enhance breast cancer metastasis through IL5 and GM-CSF

Joyce and colleagues report that obesity promotes lung neutrophilia in mice, which in the presence of a primary breast tumour fosters metastasis to the lung in a manner dependent on GM-CSF and IL5.

Daniela F. Quail
Oakley C. Olson
Johanna A. Joyce
Research24 Jul 2017
Nature Cell Biology

Volume: 19, P: 974-987
Targeted repositioning identifies drugs that increase fibroblast growth factor 20 production and protect against 6-hydroxydopamine-induced nigral cell loss in rats

Edward J. R. Fletcher
Aran D. Jamieson
Susan Duty
ResearchOpen Access06 Jun 2019
Scientific Reports

Volume: 9, P: 1-9
Adaptive speed control of BLDC motors for enhanced electric vehicle performance using fuzzy logic

R. Shenbagalakshmi
Shailendra Kumar Mittal
Krishnaraj Ramaswamy
ResearchOpen Access12 Apr 2025
Scientific Reports

Volume: 15, P: 1-22
In vitro antioxidant and antibacterial activities of biogenic synthesized zinc oxide nanoparticles using leaf extract of Mallotus philippinensis Mull. Arg

Arun Kumar Khajuria
Anuj Kandwal
Archana Bachheti
ResearchOpen Access24 Feb 2025
Scientific Reports

Volume: 15, P: 1-18
Choroidal abnormalities in birdshot chorioretinopathy: An indocyanine green angiography study

L J Howe
M R Stanford
J Marshall
Research01 Jul 1997
Eye

Volume: 11, P: 554-559
Observation of the rare B_s⁰ →µ⁺µ⁻ decay from the combined analysis of CMS and LHCb data

Combined analysis of proton-proton collision data from the Large Hadron Collider at CERN by the CMS and LHCb collaborations leads to the observation of the extremely rare decay of the strange B meson into muons; the result is compatible with the standard model of particle physics, and does not show any signs of new physics, such as supersymmetry.

V. Khachatryan
A.M. Sirunyan
E. Pesen
ResearchOpen Access13 May 2015
Nature

Volume: 522, P: 68-72
Effect of residue and weed management practices on weed flora, yield, energetics, carbon footprint, economics and soil quality of zero tillage wheat

R. Puniya
B. R. Bazaya
Swati Mehta
ResearchOpen Access07 Nov 2023
Scientific Reports

Volume: 13, P: 1-15
Genomic autopsy to identify underlying causes of pregnancy loss and perinatal death

In a new study including 200 families who experienced perinatal death, adding genomic analyses to standard autopsies improved the identification of underlying pathogenic causes and informed genetic counseling.

Alicia B. Byrne
Peer Arts
Hamish S. Scott
ResearchOpen Access19 Jan 2023
Nature Medicine

Volume: 29, P: 180-189
Correlating COVID-19 severity with biomarker profiles and patient prognosis

R. C. S. Danielle
D. M. Débora
D. L. Iúri
ResearchOpen Access27 Sept 2024
Scientific Reports

Volume: 14, P: 1-14
Linkers made to measure

Members of the family of fungal Zn₂Cys₆ DNA-binding proteins discriminate between their DNA targets using neither their DNA-binding module, nor their dimerization domain, but primarily through the relatively flexible linker between them.

John W.R. Schwabe
Daniela Rhodes
News & Views01 Sept 1997
Nature Structural Biology

Volume: 4, P: 680-683
A framework for national scenarios with varying emission reductions

There is no common structure for the way national emissions scenarios are created, hindering efforts for comparison and analysis at the larger scale. This Perspective presents a framework to guide individual national scenario creation in a standardized way.

Shinichiro Fujimori
Volker Krey
Keywan Riahi
Reviews27 May 2021
Nature Climate Change

Volume: 11, P: 472-480
A phase II study of single-agent gefitinib as first-line therapy in patients with stage IV non-small-cell lung cancer

R Suzuki
Y Hasegawa
K Shimokata
ResearchOpen Access02 May 2006
British Journal of Cancer

Volume: 94, P: 1599-1603
Probing the role of multicellular organization in three-dimensional microenvironments

Dirk R Albrecht
Gregory H Underhill
Sangeeta N Bhatia
Research20 Apr 2006
Nature Methods

Volume: 3, P: 369-375
Why the prostate arm of the PLCO trial failed and what it has taught us

Given a recent update from the PLCO trial reporting that over 90% of men in the 'usual care' arm underwent some degree of PSA testing, the PLCO can no longer accurately be called a trial of screening versus no screening — nor can it be included as such in meta-analyses or guideline statements.

Matthew R. Cooperberg
News & Views12 Jul 2016
Nature Reviews Urology

Volume: 13, P: 439-440
Digital health technologies in the accelerating medicines Partnership® Schizophrenia Program

Johanna T. W. Wigman
Ann Ee Ching
John Torous
ResearchOpen Access03 Jun 2025
Schizophrenia

Volume: 11, P: 1-10
Mesna ameliorates acute lung injury induced by intestinal ischemia–reperfusion in rats

Samia Adel Abd El-Baset
Manal R. Abd El-haleem
Asmaa A. A. Kattaia
ResearchOpen Access25 Jun 2021
Scientific Reports

Volume: 11, P: 1-14
Translation-dependent displacement of UPF1 from coding sequences causes its enrichment in 3′ UTRs

The RNA helicase UPF1 has been implicated in various functions including nonsense-mediated decay (NMD). Transcriptome-wide analysis of UPF1-binding sites in translationally active versus inhibited cells provides evidence for translation-independent UPF1-RNA interactions and also suggests that UPF1 bound to coding sequence may be displaced by translating ribosomes and that NMD substrate selection may occur after UPF1-RNA interaction.

David Zünd
Andreas R Gruber
Oliver Mühlemann
Research07 Jul 2013
Nature Structural & Molecular Biology

Volume: 20, P: 936-943
Systemic fungal infection is associated with the development of retinopathy of prematurity in very low birth weight infants: a meta-review

S K Bharwani
R Dhanireddy
Research29 Nov 2007
Journal of Perinatology

Volume: 28, P: 61-66
Author Correction: The REACH radiometer for detecting the 21-cm hydrogen signal from redshift z ≈ 7.5–28

E. de Lera Acedo
D. I. L. de Villiers
K. Zarb-Adami
Amendments and Corrections03 Oct 2022
Nature Astronomy

Volume: 6, P: 1332
Unified regression model of binding equilibria in crowded environments

Byoungkoo Lee
Philip R. LeDuc
Russell Schwartz
ResearchOpen Access20 Sept 2011
Scientific Reports

Volume: 1, P: 1-11
Structural basis for human respiratory syncytial virus NS1-mediated modulation of host responses

This study reports the structure of hRSV NS1, identifying unique regions that modulate host gene expression and contribute to inhibition of the IFN-I pathway and of dendritic cell maturation, pointing to new avenues of hRSV attenuation.

Srirupa Chatterjee
Priya Luthra
Daisy W. Leung
Research30 Jun 2017
Nature Microbiology

Volume: 2, P: 1-8
Quantification of narrow band UVB radiation doses in phototherapy using diacetylene based film dosimeters

Apoorva Mittal
Manoj Kumar
Akhilesh K. Verma
ResearchOpen Access12 Jan 2021
Scientific Reports

Volume: 11, P: 1-9
Cognitive assessment in the Accelerating Medicines Partnership® Schizophrenia Program: harmonization priorities and strategies in a diverse international sample

Kelly Allott
Walid Yassin
William S. Stone
ResearchOpen Access24 Mar 2025
Schizophrenia

Volume: 11, P: 1-12
The MR neuroimaging protocol for the Accelerating Medicines Partnership® Schizophrenia Program

Michael P. Harms
Kang-Ik K. Cho
Ofer Pasternak
ResearchOpen Access02 Apr 2025
Schizophrenia

Volume: 11, P: 1-14
Sample ascertainment and clinical outcome measures in the Accelerating Medicines Partnership® Schizophrenia Program

Jean Addington
Lu Liu
Alison R. Yung
ResearchOpen Access03 Apr 2025
Schizophrenia

Volume: 11, P: 1-10
Data analysis strategies for the Accelerating Medicines Partnership® Schizophrenia Program

Nora Penzel
Pablo Polosecki
Ofer Pasternak
ResearchOpen Access03 Apr 2025
Schizophrenia

Volume: 11, P: 1-15
Author Correction: A portrait of the Higgs boson by the CMS experiment ten years after the discovery

A. Tumasyan
W. Adam
A. Zhokin
Amendments and CorrectionsOpen Access18 Oct 2023
Nature

Volume: 623, P: E4
Publisher Correction: Observation of triple J/ψ meson production in proton-proton collisions

A. Tumasyan
W. Adam
W. Vetens
Amendments and CorrectionsOpen Access12 Dec 2023
Nature Physics

Volume: 20, P: 332
Enabling FAIR data stewardship in complex international multi-site studies: Data Operations for the Accelerating Medicines Partnership® Schizophrenia Program

Tashrif Billah
Kang Ik K. Cho
Sylvain Bouix
ResearchOpen Access03 Apr 2025
Schizophrenia

Volume: 11, P: 1-11
A pigeonpea gene confers resistance to Asian soybean rust in soybean

Soybean is made resistant to Asian soybean rust using a gene cloned from pigeonpea, showing that legumes may contain a reservoir of disease-resistance genes.

Cintia G Kawashima
Gustavo Augusto Guimarães
Sérgio H Brommonschenkel
Research25 Apr 2016
Nature Biotechnology

Volume: 34, P: 661-665
Publisher Correction: Observation of triple J/ψ meson production in proton-proton collisions

A. Tumasyan
W. Adam
W. Vetens
Amendments and CorrectionsOpen Access27 Feb 2023
Nature Physics

Volume: 19, P: 461
Technology Insight: clinical role of magnetic resonance angiography in the diagnosis and management of renal artery stenosis

Improvement is still needed in the diagnosis of renal artery stenosis, which is the most common treatable cause of secondary hypertension. An accurate functional and morphological characterization of the disease might assist in management of patients. The value of magnetic resonance angiography in this setting is discussed.

Santo Dellegrottaglie
Javier Sanz
Sanjay Rajagopalan
Reviews01 Jun 2006
Nature Clinical Practice Cardiovascular Medicine

Volume: 3, P: 329-338
Circulating levels of colony-stimulating factor 1 as a prognostic indicator in 82 patients with epithelial ovarian cancer

SM Scholl
CH Bascou
ER Stanley
Research01 Feb 1994
British Journal of Cancer

Volume: 69, P: 342-346
Identification of unique neoantigen qualities in long-term survivors of pancreatic cancer

The analysis of T-cell antigens in long-term survivors of pancreatic ductal adenocarcinoma suggests that neoantigen immunogenicity and quality, not purely quantity, correlate with survival.

Vinod P. Balachandran
Marta Łuksza
Steven D. Leach
Research01 Nov 2017
Nature

Volume: 551, P: 512-516
The detection of alkylation damage in the DNA of human gastrointestinal tissues

CN Hall
AF Badawi
R Saffhill
Research01 Jul 1991
British Journal of Cancer

Volume: 64, P: 59-63

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