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Showing 101–150 of 273 results

Advanced filters: Author: R J Reiter Clear advanced filters

Standardization and harmonization of distributed multi-center proteotype analysis supporting precision medicine studies

Distributed multi-omic digitization of clinical specimen across multiple sites is a prerequisite for turning molecular precision medicine into reality. Here, the authors show that coordinated proteotype data acquisition is feasible using standardized MS data acquisition and analysis strategies.

Yue Xuan
Nicholas W. Bateman
Thomas P. Conrads
ResearchOpen Access16 Oct 2020
Nature Communications

Volume: 11, P: 1-12
Genetic variation at MECOM, TERT, JAK2 and HBS1L-MYB predisposes to myeloproliferative neoplasms

Somatic mutations drive the clonal proliferation of myeloproliferative neoplasms. Here the authors conduct a genome-wide association study and identify germline variation at multiple loci associated with the development and disease phenotype of these cancers.

William Tapper
Amy V. Jones
Nicholas C.P. Cross
ResearchOpen Access07 Apr 2015
Nature Communications

Volume: 6, P: 1-11
Publisher Correction: Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs

Matthew R. Golder
Jenny Liu
Jeremiah A. Johnson
Amendments and Corrections03 Sept 2018
Nature Biomedical Engineering

Volume: 2, P: 707
Clonal dynamics of haematopoiesis across the human lifespan

Haematopoiesis has high clonal diversity up to about 65 years of age, after which diversity drops precipitously owing to positive selection acting on a handful of clones that expand exponentially throughout adulthood.

Emily Mitchell
Michael Spencer Chapman
Peter J. Campbell
ResearchOpen Access01 Jun 2022
Nature

Volume: 606, P: 343-350
Retest variability and patient reliability indices of quantitative fundus autofluorescence in age-related macular degeneration: a MACUSTAR study report

Leon von der Emde
Merten Mallwitz
Thomas Ach
ResearchOpen Access13 Oct 2023
Scientific Reports

Volume: 13, P: 1-12
Prioritized mass spectrometry increases the depth, sensitivity and data completeness of single-cell proteomics

Prioritized Single-Cell ProtEomics (pSCoPE) introduces the concept of using priority levels that define the temporal order of peptide analysis for single-cell proteomic analysis. Prioritized data acquisition aims to simultaneously optimize the consistency, sensitivity, depth and accuracy of protein quantification.

R. Gray Huffman
Andrew Leduc
Nikolai Slavov
ResearchOpen Access03 Apr 2023
Nature Methods

Volume: 20, P: 714-722
Studies of pear-shaped nuclei using accelerated radioactive beams

An experimental study of certain short-lived isotopes of radon and radium has found clear octupole deformation in the nuclei of the latter — that is, these nuclei are pear-shaped; the results enable discrimination between differing theoretical approaches to octupole correlations.

L. P. Gaffney
P. A. Butler
M. Zielinska
Research08 May 2013
Nature

Volume: 497, P: 199-204
In vivo modulation of endothelial polarization by Apelin receptor signalling

Endothelial cells align in the direction of flow in response to shear stress. Here the authors describe a zebrafish model for visualization of endothelial polarization and demonstrate that endothelial cell alignment depends on blood flow and Apelin signalling.

Hyouk-Bum Kwon
Shengpeng Wang
Didier Y. R. Stainier
ResearchOpen Access01 Jun 2016
Nature Communications

Volume: 7, P: 1-12
CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids

Although lipids are known to affect Hedgehog (Hh) signalling, the underlying mechanisms remain unclear. Here, the authors show that Canopy4 regulates membrane sterol lipid levels, with knockout mouse embryos exhibiting digit number changes and other Hh signalling-related developmental defects.

Megan Lo
Amnon Sharir
Ophir D. Klein
ResearchOpen Access03 May 2022
Nature Communications

Volume: 13, P: 1-13
177 CONTROLLED, RANDOMIZED MULTICENTER CLINICAL TRIAL OF HIGH-DOSE VERSUS LOW-DOSE BOVINE SURFACTANT VERY PREMATURE INFANTS

L Gortner
U Bernsau
H Versmold
Research01 Dec 1991
Pediatric Research

Volume: 30, P: 657
Vertebrate Smoothened functions at the primary cilium

Kevin C. Corbit
Pia Aanstad
Jeremy F. Reiter
Research31 Aug 2005
Nature

Volume: 437, P: 1018-1021
Reduction of liver fibrosis by rationally designed macromolecular telmisartan prodrugs

Macromolecular telmisartan prodrugs optimized for preferential release in fibrotic liver tissue reduce liver fibrosis in mouse models, and are retained and well tolerated in the liver tissue of rats and dogs.

Matthew R. Golder
Jenny Liu
Jeremiah A. Johnson
Research20 Aug 2018
Nature Biomedical Engineering

Volume: 2, P: 822-830
The Effects of Ethanol on Striatal Dopamine and Frontal Cortical D-[³H]Aspartate Efflux Oscillate with Repeated Treatment

Anthony R Caggiula
Seymour M Antelman
Donna Kocan
Research01 Aug 1996
Neuropsychopharmacology

Volume: 15, P: 125-132
GROWTH HORMONE (GH) RELEASE IN CHILDREN WITH SHORT STATURE: STIMULATION BY HUMAN PANCREATIC TUMOR GROWH HORMONE RELEASING FACTOR-40 (hpGRF-40)

A D Rogol
R M Blizzard
M O Thorner
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 175
Immunochemotherapy with interleukin-2, interferon- α and 5-fluorouracil for progressive metastatic renal cell carcinoma: a multicenter phase II study

C M L van Herpen
R L H Jansen
P H M De Mulder
ResearchOpen Access20 Jan 2000
British Journal of Cancer

Volume: 82, P: 772-776
Allogeneic bone marrow transplantation for a subset of children with acute lymphoblastic leukemia in third remission: a conceivable alternative?

A Borgmann
E Baumgarten
G Henze
Research01 Dec 1997
Bone Marrow Transplantation

Volume: 20, P: 939-944
Structural basis of potent Zika–dengue virus antibody cross-neutralization

Monoclonal antibodies isolated from patients with dengue virus infection also bind to the Zika virus E protein and neutralize both Zika and dengue virus infection; the structures of two of these antibodies in complex with the Zika virus envelope protein define the binding determinants of the epitope and identify the structural basis of antibody cross neutralization.

Giovanna Barba-Spaeth
Wanwisa Dejnirattisai
Félix A. Rey
Research23 Jun 2016
Nature

Volume: 536, P: 48-53
HORMONAL REGULATION OF SOMATOMEDIN SECRETION BY FETAL RAT HEPATOCYTES IN CULTURE

Robert A Richman
Mark R Benedict
Barbara A Toly
Research01 Apr 1984
Pediatric Research

Volume: 18, P: 175
Evolution and Man's Place in Nature

A. R. W.
Books & Arts23 Feb 1893
Nature

Volume: 47, P: 385-386
A novel atypical sperm centriole is functional during human fertilization

The two zygote centrioles are paternally inherited; however, their development is incompletely understood. Here, the authors show that the distal centriole is remodeled into an atypical centriole which functions as the zygote’s second centriole.

Emily L. Fishman
Kyoung Jo
Tomer Avidor-Reiss
ResearchOpen Access07 Jun 2018
Nature Communications

Volume: 9, P: 1-12
Stabilizing a metalloid {Zn₁₂} unit within a polymetallide environment in [K₂Zn₂₀Bi₁₆]⁶⁻

Low-valent zinc clusters, though exceedingly rare, are appealing synthetic targets because there is evidence that they may show unconventional chemical and physical behavior. Here, the authors obtain a large heterometallic zinc-bismuth cluster anion and discover that it bears a metalloid {Zn₁₂} core with four-center bonding and essentially zero-valent character.

Armin R. Eulenstein
Yannick J. Franzke
Stefanie Dehnen
ResearchOpen Access12 Oct 2020
Nature Communications

Volume: 11, P: 1-8
Multicomponent reactions provide key molecules for secret communication

Designing molecular keys and combining advanced encryption standard cryptography with molecular steganography is a secure way for encoding messages. Here, the authors use the Ugi four-component reaction of perfluorinated acids to create a library of 500,000 molecular keys for encryption and decryption.

Andreas C. Boukis
Kevin Reiter
Michael A. R. Meier
ResearchOpen Access12 Apr 2018
Nature Communications

Volume: 9, P: 1-10
GM-CSF can improve the cytogenetic response obtained with interferon-alpha therapy in patients with chronic myelogenous leukemia

J Cortes
H Kantarjian
M Talpaz
Research04 Jun 1998
Leukemia

Volume: 12, P: 860-864
Delineation of a 6 cM commonly deleted region in childhood acute lymphoblastic leukemia on the 6q chromosomal arm

B Gérard
H Cavé
B Grandchamp
Research01 Feb 1997
Leukemia

Volume: 11, P: 228-232
81 EVALUATION OF GRF TEST IN GH-DEFICIENT CHILDREN

L Cavallo
A Acquafredda
L Piacente
Research01 Oct 1988
Pediatric Research

Volume: 24, P: 530
Prognosis and quality of life in patients with locally advanced rectal cancer after abdominoperineal resection in the CAO/ARO/AIO-04 randomized phase 3 trial

Jochen Gaedcke
Malte Sahrhage
H. Leber
ResearchOpen Access13 Feb 2025
Scientific Reports

Volume: 15, P: 1-12
Allelic loss of 10q23, the PTEN tumour suppressor gene locus, in Barrett’s oesophagus-associated adenocarcinoma

M H Kulke
R D Odze
C Eng
ResearchOpen Access20 Mar 2001
British Journal of Cancer

Volume: 84, P: 748-753
82 RESPONSIVENESS OF PITUTARY hGH TO CRF IN JUNVENILES WITH SIMPLE OBESITY

F Galluzzi
R Salti
E Cacciari
Research01 Oct 1988
Pediatric Research

Volume: 24, P: 530
Substantial π-aromaticity in the anionic heavy-metal cluster [Th@Bi₁₂]⁴⁻

A wide variety of organic and inorganic compounds show π-aromaticity, yet for all-metal systems it has remained restricted to compounds with three to five atoms. Now, the anionic cluster [Th@Bi₁₂]⁴⁻ has been shown to exhibit π-aromaticity, with a significant ring current despite relying on the delocalization of only two π-electrons.

Armin R. Eulenstein
Yannick J. Franzke
Stefanie Dehnen
Research07 Dec 2020
Nature Chemistry

Volume: 13, P: 149-155
Questions of evolution

S. R. Kulkarni
S. E. Thorsett
News & Views12 Aug 1993
Nature

Volume: 364, P: 579-580
Depletion on volcanic aerosols

R. L. Jones
News & Views27 Jul 1989
Nature

Volume: 340, P: 269-270
Differing associations of PM_2.5 exposure with systolic and diastolic blood pressures across exposure durations in a predominantly non-Hispanic Black cohort

Jiajun Luo
Rena R. Jones
Briseis Aschebrook-Kilfoy
ResearchOpen Access31 Aug 2024
Scientific Reports

Volume: 14, P: 1-11
ACQUIRED AGAMMAGLOBULINEMIA IN 3 RELATED MALE CHILDREN FOLLOWING AN ILLNESS WITH CLINICAL AND LABORATORY FEATURES OF INFECTIOUS MONONUCLEOSIS

A J Provisor
J J Iacuone
M Green
Research01 Apr 1974
Pediatric Research

Volume: 8, P: 417
329 II-DESOXYCORTICOSTERONE (DOC) AND 18-HYDROXY-DOC(18-OH-DOC) IN JUVENILE HYPERTENSION

W Rauh
R Lustig
M I New
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 418
The low frequency of clinical resistance to PDGFR inhibitors in myeloid neoplasms with abnormalities of PDGFRA might be related to the limited repertoire of possible PDGFRA kinase domain mutations in vitro

N von Bubnoff
S P Gorantla
J Duyster
Research25 Oct 2010
Oncogene

Volume: 30, P: 933-943
Publisher Correction: The observation of vibrating pear-shapes in radon nuclei

P. A. Butler
L. P. Gaffney
M. Zielinska
Amendments and CorrectionsOpen Access09 Oct 2020
Nature Communications

Volume: 11, P: 1
Calcium-ATPase Activity in Cystic Fibrosis Erythrocyte Membranes: Decreased Activity in Patients with Pancreatic Insufficiency

Dorr G Dearborn
Robert J Wityk
Robert C Stern
Research01 Sept 1984
Pediatric Research

Volume: 18, P: 890-895
Cell types of origin of the cell-free transcriptome

Cell types affected by various diseases are inferred from cell-free RNA.

Sevahn K. Vorperian
Mira N. Moufarrej
Stephen R. Quake
ResearchOpen Access07 Feb 2022
Nature Biotechnology

Volume: 40, P: 855-861
57 Role of Nitric Oxide on Oxidative Stress of Newborn. Experimental Study

E Gitto
R J Reiter
Ignazio Barberi
Research01 Aug 2005
Pediatric Research

Volume: 58, P: 364
Lens development

J W McAvoy
C G Chamberlain
F J Lovicu
Research01 May 1999
Eye

Volume: 13, P: 425-437
FRUCTOSE 1. 6-DIPHOSPHATASE AND GLUCOSE 6-PHOSPHATASE IN NEWBORN RATS WITH INTRAUTERINE GROWTH RETARDATION

Sharon R Siegel
William Oh
Delbert A Fisher
Research01 Apr 1977
Pediatric Research

Volume: 11, P: 521
A novel BCR-ABL rearrangement in a Philadelphia chromosome-positive chronic myelogenous leukaemia variant with thrombocythaemia

R Rubinstein
LR Purves
Research28 Apr 1998
Leukemia

Volume: 12, P: 230-232
VIROLOGIC STUDIES IN CHILDHOOD CONNECTIVE TISSUE DISEASES (CTD)

P Phillips
P Parkman
W Lim
Research01 Apr 1974
Pediatric Research

Volume: 8, P: 417
An APRIL to remember: novel TNF ligands as therapeutic targets

Two of the newest members of the tumour-necrosis factor family, BLyS and APRIL, are crucial in B-cell development and survival, and are implicated in autoimmune diseases and cancer. Dillon and colleagues review APRIL biology, and compare potential therapeutics that target APRIL and/or BLyS.

Stacey R. Dillon
Jane A. Gross
Anne J. Novak
Reviews10 Feb 2006
Nature Reviews Drug Discovery

Volume: 5, P: 235-246
Detection of genomic regions differentiating two closely related oak species Quercus petraea (Matt.) Liebl. and Quercus robur L.

C Bodénès
S Joandet
A Kremer
Research01 Apr 1997
Heredity

Volume: 78, P: 433-444
Identification of glioma-associated antigen MUC 2-63 as CD44

P Romeijn
R Lenthall
MA Ritter
Research01 Nov 1994
British Journal of Cancer

Volume: 70, P: 799-803
1229 LONG TERM GASTROINTESTINAL AND NUTRITIONAL ASSESSMENT OF INFANTS WITH NECROTIZING ENTEROCOLITIS (NEC)

S Abbasl
S Duara
G R Pereira
Research01 Apr 1981
Pediatric Research

Volume: 15, P: 647
Resistance of ovarian teratocarcinoma cell spheroids to complement-mediated lysis

L Bjørge
S Junnikkala
S Meri
Research01 May 1997
British Journal of Cancer

Volume: 75, P: 1247-1255
334 CEREBROSPINAL FLUID (CSF) 6 INTERFERON (INF) TUMOUR NECROSIS FACTOR-α (TNF) AND INTERLEUKIN-1β (1L-lβ) CONCENTRATIONS IN CHILDREN WITH TUBERCULOUS MENINGITIS (TBM)

Peter R Donald
Johan F Schoeman
George H Mccracken
Research01 Jul 1994
Pediatric Research

Volume: 36, P: 58
Antibodies to Human HSP60 in Patients with Juvenile Chronic Arthritis, Diabetes Mellitus, and Cystic Fibrosis

E R de Graeff-Meeder
G T Rijkers
B J M Zegers
Research01 Oct 1993
Pediatric Research

Volume: 34, P: 424-428

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