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Showing 101–150 of 422 results

Advanced filters: Author: R Nishimura Clear advanced filters

A dual molecular analogue tuner for dissecting protein function in mammalian cells

Loss-of-function approaches are fundamental for dissecting the roles played by genes but methods to simultaneously perturb several proteins in the same mammalian cell are scarce. Here the authors harness the plant auxin and jasmonate hormone-degradation pathways and RNAi technology, to control the levels of two proteins and validate its application in stem cells.

Ran Brosh
Iryna Hrynyk
Ihor R. Lemischka
ResearchOpen Access27 May 2016
Nature Communications

Volume: 7, P: 1-13
Trace element abundances in basalts of Nauru Basin

R. Batiza
R. L. Larson
H. Tokuyama
Research31 Jul 1980
Nature

Volume: 286, P: 476-478
A pseudoknotted RNA oligonucleotide

Joseph D. Puglisi
Jacqueline R. Wyatt
Ignacio Tinoco Jr.
Research21 Jan 1988
Nature

Volume: 331, P: 283-286
The B-cell surface protein CD72/Lyb-2 is the ligand for CDS

Hilde Van de Velde
Ilka von Hoegen
Kris Thielemans
Research20 Jun 1991
Nature

Volume: 351, P: 662-665
Cosmic-ray electrons and galactic radio emission—a conflict?

G. D. BADHWAR
R. R. DANIEL
S. A. STEPHENS
Research01 Feb 1977
Nature

Volume: 265, P: 424-426
Adrenergic activation of triiodothyronine production in brown adipose tissue

J. E. Silva
P. R. Larsen
Research20 Oct 1983
Nature

Volume: 305, P: 712-713
Key residues involved in calcium-binding motifs in EGF-like domains

P. A. Handford
M. Mayhew
G. G. Brownlee
Research09 May 1991
Nature

Volume: 351, P: 164-167
Recent Climatic Change and Increased Glacierization in the Eastern Canadian Arctic

R. S. BRADLEY
G. H. MILLER
Research16 Jun 1972
Nature

Volume: 237, P: 385-387
Spatial distribution of γ-ray bursts observed by BATSE

C. A. Meegan
G. J. Fishman
C. Kouveliotou
Research09 Jan 1992
Nature

Volume: 355, P: 143-145
Narrow-band observations of galactic and extragalactic sources at 1 mm

P. E. CLEGG
P. A. R. ADE
M. ROWAN-ROBINSON
Research07 Jun 1974
Nature

Volume: 249, P: 530-532
Long-term climatic changes indicated by crystal growth in polar ice

J. R. Petit
P. Duval
C. Lorius
Research01 Mar 1987
Nature

Volume: 326, P: 62-64
Search for Anti-matter in Primary Cosmic Rays

J. G. GREENHILL
A. R. CLARKE
H. ELLIOT
Research19 Mar 1971
Nature

Volume: 230, P: 170-172
Sequencing of 16S–23S spacer in a ribosomal RNA operon of Euglena gracilis chloroplast DNA reveals two tRNA genes

L. Graf
H. Kössel
E. Stutz
Research28 Aug 1980
Nature

Volume: 286, P: 908-910
2H-Thiopyran-2-thione sulfine, a compound for converting H₂S to HSOH/H₂S₂ and increasing intracellular sulfane sulfur levels

Reactive sulfane sulfur species such as persulfides and H₂S₂ are important redox regulators and linked to H₂S signaling, but their study is hindered by a lack of suitable donors to produce them. Here, the authors report 2H-thiopyran-2-thione sulfine (TTS), a compound which can specifically convert H₂S to HSOH, and then to H₂S₂ in the presence of excess H₂S.

Qi Cui
Meg Shieh
Ming Xian
ResearchOpen Access19 Mar 2024
Nature Communications

Volume: 15, P: 1-13
A rapid energetic X-ray flare in the quasar PKS0558–504

R. A. Remillard
B. Grossan
Y. Tanaka
Research18 Apr 1991
Nature

Volume: 350, P: 589-592
Intramolecular photochemical electron transfer in a linked porphyrin–quinone molecule as a model for the primary step of photosynthesis

Te-Fu Ho
Alan R. McIntosh
James R. Bolton
Research17 Jul 1980
Nature

Volume: 286, P: 254-256
Contribution of hydrophobic interactions to protein stability

James T. Kellis Jr
Kerstin Nyberg
Alan R. Fersht
Research23 Jun 1988
Nature

Volume: 333, P: 784-786
Reversible isothermal sorption of hydrogen by tungsten trioxide in presence of platinum

Allan R. Berzins
Paul A. Sermon
Research01 Jun 1983
Nature

Volume: 303, P: 506-508
Increased intracellular cyclic GMP does not correlate with protein discharge from pancreatic acinar cells

GARY R. GUNTHER
JAMES D. JAMIESON
Research26 Jul 1979
Nature

Volume: 280, P: 318-320
X-ray identification of the soft γ-ray repeater 1806 – 20

T. Murakami
Y. Tanaka
A. Yoshida
Research10 Mar 1994
Nature

Volume: 368, P: 127-129
Evolutionary origin of 5.8S ribosomal RNA

R. J. CEDERGREN
DAVID SANKOFF
Research04 Mar 1976
Nature

Volume: 260, P: 74-75
Photochemical cis–trans isomerisation of bovine rhodopsin at liquid helium temperatures

B. ATON
R. H. CALLENDER
B. HONIG
Research29 Jun 1978
Nature

Volume: 273, P: 784-786
Defect of macrophage function in the antibody response to sheep erythrocytes in systemic Mycobacterium lepraemurium infection

SUSAN R. WATSON
V. S. ŠLJIVIĆ
I. N. BROWN
Research17 Jul 1975
Nature

Volume: 256, P: 206-208
Cytological Studies of the Pathogenesis of Chronic Lymphatic Leukaemia

S. ALBERT
G. W. MOORE
P. L. WOLF
Research01 Nov 1967
Nature

Volume: 216, P: 491-493
Oxidative DNA damage through long-range electron transfer

Daniel B. Hall
R. Erik Holmlin
Jacqueline K. Barton
Research22 Aug 1996
Nature

Volume: 382, P: 731-735
Space weathering record and pristine state of Ryugu samples from MicrOmega spectral analysis

A statistical study of the ~2.7 µm hydration band in the Ryugu samples shows that Ryugu’s immediate subsurface has not been exposed to space weathering and that even the pristine CI chondrites exhibit terrestrial contamination, making the Hayabusa2 samples a reference for primitive water abundance in carbonaceous asteroids.

T. Le Pivert-Jolivet
R. Brunetto
S. Watanabe
Research05 Oct 2023
Nature Astronomy

Volume: 7, P: 1445-1453
A role for collagen in the pathogenesis of muscular dystrophy?

V. C. Duance
H. R. Stephens
V. Dubowitz
Research03 Apr 1980
Nature

Volume: 284, P: 470-472
Glutamate Sensitivity of Denervated Insect Muscle Fibres

P. N. R. USHERWOOD
Research26 Jul 1969
Nature

Volume: 223, P: 411-413
Exceptional high fatigue strength in Cu-15at.%Al alloy with moderate grain size

Rui Liu
Yanzhong Tian
Zhefeng Zhang
ResearchOpen Access06 Jun 2016
Scientific Reports

Volume: 6, P: 1-9
Evidence for a decline of PCBs and PAHs in rural vegetation and air in the United Kingdom

K. C. Jones
G. Sanders
A. E. Johnston
Research12 Mar 1992
Nature

Volume: 356, P: 137-140
Interaction between two homeodomain proteins is specified by a short C-terminal tail

Martha R. Stark
Alexander D. Johnson
Research29 Sept 1994
Nature

Volume: 371, P: 429-432
Concentrations of Pyruvate, Pyruvate Kinase and Lactate Dehydrogenase in the Kidney of the Alloxan-diabetic Rat

R. COULSON
J. ANDERSON
Research26 Aug 1967
Nature

Volume: 215, P: 981-982
Autozygosity mapping of Bardet–Biedl syndrome to 12q21.2 and confirmation of FLJ23560 as BBS10

Dominic R A White
Anuradha Ganesh
Eamonn R Maher
Research15 Nov 2006
European Journal of Human Genetics

Volume: 15, P: 173-178
Super-enhancer hijacking drives ectopic expression of hedgehog pathway ligands in meningiomas

Hedgehog signalling is known to be linked to oncogenic proliferation. Here, the authors identify structural events as a mechanism of Hedgehog activation in over one-third of driver unknown meningiomas.

Mark W. Youngblood
Zeynep Erson-Omay
Murat Günel
ResearchOpen Access07 Oct 2023
Nature Communications

Volume: 14, P: 1-16
Two-population model for the sources of γ-ray bursts

R. E. Lingenfelter
J. C. Higdon
Research12 Mar 1992
Nature

Volume: 356, P: 132-133
Sequences on the human Y chromosome homologous to the autosomal gene for argininosuccinate synthetase

S. P. Daiger
R. S. Wildin
T.-S. Su
Research12 Aug 1982
Nature

Volume: 298, P: 682-684
Variations of organic functional chemistry in carbonaceous matter from the asteroid 162173 Ryugu

A new study of samples from the Ryugu asteroid reveal a greater diversity of macromolecular organic matter than that found in related carbonaceous meteorites. Researchers find distinct populations of alkyl-aromatic grains, and organic carbonate is found with coarse-grained clay minerals

Bradley De Gregorio
George D. Cody
Yuichi Tsuda
ResearchOpen Access29 Aug 2024
Nature Communications

Volume: 15, P: 1-11
Plasma binding of vitamin B₆ compounds

B. B. ANDERSON
P. A. NEWMARK
R. GREEN
Research09 Aug 1974
Nature

Volume: 250, P: 502-504
Contribution of Ryugu-like material to Earth’s volatile inventory by Cu and Zn isotopic analysis

A comparison of copper and zinc isotopic measurements between the Ryugu samples and various carbonaceous chondrites excludes any genetic link between the two except for the CI (Ivuna-type) chondrites. Ryugu-like material might have accounted for ~5% of Earth’s mass.

Marine Paquet
Frederic Moynier
Hisayoshi Yurimoto
Research12 Dec 2022
Nature Astronomy

Volume: 7, P: 182-189
A class-mismatched TCR bypasses MHC restriction via an unorthodox but fully functional binding geometry

MHC restriction depicts CD4⁺ T cell activation by MHC-II and CD8A⁺ by MHC-I, but rare T cells with mismatched MHC restriction have been reported. Here the authors use crystallography to describe features of such a mismatched TCR-MHC interaction and implicate an atypical TCR structure and TCR-MHC interface as contributing factors.

Nishant K. Singh
Jesus A. Alonso
Brian M. Baker
ResearchOpen Access23 Nov 2022
Nature Communications

Volume: 13, P: 1-14
Fluid flow-induced left-right asymmetric decay of Dand5 mRNA in the mouse embryo requires a Bicc1-Ccr4 RNA degradation complex

Questioning what regulates left-right asymmetry breaking in the mouse node: the authors identify a 200 bp stretch of the Dand5 3’UTR where Bicc1 binds, and Cnot proteins downstream of calcium flow regulate the post-transcriptional regulation of Dand5 by Bicc1.

Katsura Minegishi
Benjamin Rothé
Hiroshi Hamada
ResearchOpen Access01 Jul 2021
Nature Communications

Volume: 12, P: 1-17
TMIGD2 is an orchestrator and therapeutic target on human acute myeloid leukemia stem cells

The immune receptor Transmembrane and immunoglobulin domain containing 2 (TMIGD2) mediates T-cell and nature killer cells co-stimulation upon B7-family HHLA2 engagement. Here, the authors show that TMIGD2 is expressed in Acute Myeloid Leukaemia stem cells regulating self-renewal and differentiation to facilitate leukemogenesis.

Hao Wang
R. Alejandro Sica
Xingxing Zang
ResearchOpen Access02 Jan 2024
Nature Communications

Volume: 15, P: 1-17
Ground deformation reveals the scale-invariant conduit dynamics driving explosive basaltic eruptions

Here, the authors use 20 years of ground deformation data from Stromboli and correlate this data with eruptive records. They find that duration and amplitude of the inflation trend scales with eruption magnitude, indicating that explosive dynamics obeys the same (scale-invariant) conduit process.

M. Ripepe
G. Lacanna
D. Delle Donne
ResearchOpen Access16 Mar 2021
Nature Communications

Volume: 12, P: 1-8
Presenilin mutations associated with Alzheimer disease cause defective intracellular trafficking of β-catenin,a component of the presenilin protein complex

M. Nishimura
G. Yu
P. St George–Hyslop
Research01 Feb 1999
Nature Medicine

Volume: 5, P: 164-169
Cross-resistance to cytotoxic drugs in human glioma cell lines in culture

S Merry
S B Kaye
R I Freshney
Research01 Dec 1984
British Journal of Cancer

Volume: 50, P: 831-835
Influx of nitrogen-rich material from the outer Solar System indicated by iron nitride in Ryugu samples

Iron nitride (Fe₄N) is detected on magnetite particles within the Ryugu sample returned by Hayabusa2. It is probably the product of impacts of nitrogen-rich dust from the outer Solar System on the surface of Ryugu, indicative of a flux of N-rich dust in the inner Solar System.

Toru Matsumoto
Takaaki Noguchi
Yuichi Tsuda
ResearchOpen Access30 Nov 2023
Nature Astronomy

Volume: 8, P: 207-215
Neurotensin increases mortality and mast cells reduce neurotensin levels in a mouse model of sepsis

Adrian M Piliponsky
Ching-Cheng Chen
Stephen J Galli
Research30 Mar 2008
Nature Medicine

Volume: 14, P: 392-398
T-ing up inflammation in fat

Obesity generates a proinflammatory environment in adipose tissue, but the factors that initiate this inflammatory cascade have been unclear. Three studies now show that alterations in the composition of adipose tissue T cells occur early in obesity and shape the relationship between immunity and metabolism (pages 914–920, 921–929 and 930–939).

Carey N. Lumeng
Ivan Maillard
Alan R. Saltiel
News & Views01 Aug 2009
Nature Medicine

Volume: 15, P: 846-847
Control of seed dormancy and germination by DOG1-AHG1 PP2C phosphatase complex via binding to heme

The hormone abscisic acid (ABA) prevents seeds from germination when conditions are not suitable. Here the authors show that DOG1, a positive regulator of germination, impairs ABA signaling via genetic and physical interactions with the AHG1 phosphatase and that DOG1 binding to heme is required for this activity.

Noriyuki Nishimura
Wataru Tsuchiya
Toshimasa Yamazaki
ResearchOpen Access06 Jun 2018
Nature Communications

Volume: 9, P: 1-14
‘SCREENING OF OUTPATIENT POPULATION FOR RENAL DISEASE’

K P Mehta
K I Acharya
G S Hathi
Research01 Aug 1980
Pediatric Research

Volume: 14, P: 983

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