In vitro experiments of a biomaterial's degradability rarely predict its in vivo behaviour. It is now shown that tracking the hydrolytic and enzymatic erosion of model materials by non-invasive fluorescence imaging allows the prediction of in vivo erosion from in vitro data. The approach should enable rapid screening of erodable biomaterials.
- Natalie Artzi
- Nuria Oliva
- Elazer R. Edelman