The main surveillance method for allograft rejection after heart transplantation is endomyocardial biopsy, but this method's invasive nature and poor uniformity of results pose problems. Noninvasive, reliable monitoring methods are, therefore, sought. In this review, protein-based and gene-based targets for the testing of allograft function to fulfill this role are discussed.
- Mandeep R Mehra
- Erika Feller
- Steve Rosenberg