Tiling describes the arrangement of neuronal processes in a pattern with little or no overlap with those of neighboring neurons. It is unclear how this is mediated in the vertebrate retina, whose mosaic cell body distribution of horizontal cells is accompanied by extensively overlapping dendrites. A study by Huckfeldt et al. now shows that the nonrandom distribution of the horizontal cells is correlated with repulsive homotypic interactions between developmentally transient processes, leading to the development of initial territories of horizontal cell.
- Rachel M Huckfeldt
- Timm Schubert
- Rachel O L Wong
