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Showing 1–6 of 6 results
Advanced filters: Author: Radhika Subramanian Clear advanced filters

  • Reconstitution studies reveal design principles by which a minimal 3-protein module differentially regulates the dynamics of spatially proximal crosslinked and noncrosslinked microtubules, mimicking microtubule array dynamics in the mitotic spindle.

    • Nandini Mani
    • Shuo Jiang
    • Radhika Subramanian
    Research
    Nature Chemical Biology
    Volume: 17, P: 964-974

  • Error-free genome segregation depends on the spindle assembly checkpoint (SAC), a signalling network that delays anaphase onset until chromosomes have established proper spindle attachments. Three reports now quantitatively examine the sensitivity and robustness of the SAC response.

    • Radhika Subramanian
    • Tarun M. Kapoor
    News & Views
    Nature Cell Biology
    Volume: 15, P: 1261-1263

  • Retinal vascular disease treatments involve frequent pharmacological intraocular administrations. Here the authors present a method to increase the half-life of injected drugs by fusing these to a hyaluronan-binding peptide, which might lead to less frequent retinal disease treatments.

    • Joy G. Ghosh
    • Andrew A. Nguyen
    • Michael Roguska
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-10