p15PAF regulates DNA replication and repair via interactions with the Proliferating Cell Nuclear Antigen (PCNA) sliding clamp. Here the authors present multi-faceted structural analyses of the p15-PCNA-DNA complex that suggests p15 regulates the sliding of PCNA along DNA during replication.
- Alfredo De Biasio
- Alain Ibáñez de Opakua
- Francisco J. Blanco