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Advanced filters: Author: Rafal Goraczniak Clear advanced filters

  • Goraczniak et al. introduce a gene-silencing method that uses 'U1 adaptors' to block polyadenylation of pre-mRNA in the nucleus. Silencing is stronger when U1 adaptors are combined with siRNAs than when either is used alone.

    • Rafal Goraczniak
    • Mark A Behlke
    • Samuel I Gunderson
    Research
    Nature Biotechnology
    Volume: 27, P: 257-263