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Showing 1–6 of 6 results

Advanced filters: Author: Rajiv R. Ratan Clear advanced filters

Inhibition versus induction of apoptosis by proteasome inhibitors depends on concentration

Kuo-I Lin
Jay M Baraban
Rajiv R Ratan
Research10 Jul 1998
Cell Death & Differentiation

Volume: 5, P: 577-583
Local cytoplasmic calcium gradients in living mitotic cells

Charles H. Keith
Rajiv Ratan
Michael L. Shelanski
Research29 Aug 1985
Nature

Volume: 316, P: 848-850
Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
Tau activation of microglial cGAS–IFN reduces MEF2C-mediated cognitive resilience

Mechanisms of cognitive resilience against Tau pathology are unknown. The authors show that inactivation of the microglial cGAS–interferon axis confers such resilience by preserving the neuronal expression of myocyte enhancer factor 2c.

Joe C. Udeochu
Sadaf Amin
Li Gan
ResearchOpen Access24 Apr 2023
Nature Neuroscience

Volume: 26, P: 737-750
Selenium abandons selenoproteins to inhibit ferroptosis rapidly

Selenium is usually incorporated into selenoproteins, with important functions in redox regulation. A new study in Nature Metabolism reveals a previously unappreciated role for selenium-based chemical species as direct electron donors to reduce ubiquinone, thus contributing to redox homeostasis by preventing lipid peroxidation.

Ian G. Chambers
Rajiv R. Ratan
News & Views13 Feb 2024
Nature Metabolism

Volume: 6, P: 200-202
Lactate is an antidepressant that mediates resilience to stress by modulating the hippocampal levels and activity of histone deacetylases

Nabil Karnib
Rim El-Ghandour
Sama F. Sleiman
Research08 Jan 2019
Neuropsychopharmacology

Volume: 44, P: 1152-1162