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Showing 1–3 of 3 results

Advanced filters: Author: Rakesh R Ramjiawan Clear advanced filters

Overcoming sorafenib evasion in hepatocellular carcinoma using CXCR4-targeted nanoparticles to co-deliver MEK-inhibitors

Yunching Chen
Ya-Chi Liu
Dan G. Duda
ResearchOpen Access09 Mar 2017
Scientific Reports

Volume: 7, P: 1-12
Antibody-mediated delivery of viral epitopes to tumors harnesses CMV-specific T cells for cancer therapy

Anti-tumor activity of cytomegalovirus (CMV)-specific CD8 T cells is achieved by antibody-mediated delivery of CMV epitopes.

David G. Millar
Rakesh R. Ramjiawan
Mark Cobbold
Research10 Feb 2020
Nature Biotechnology

Volume: 38, P: 420-425
An orthotopic mouse model of hepatocellular carcinoma with underlying liver cirrhosis

This protocol describes a syngeneic orthotopic hepatocellular carcinoma (HCC) model in immunocompetent mice with liver cirrhosis induced by carbon tetrachloride. This model recapitulates the key features of the necroinflammatory, fibrotic and angiogenic microenvironment of human HCC.

Thomas Reiberger
Yunching Chen
Dan G Duda
Protocols23 Jul 2015
Nature Protocols

Volume: 10, P: 1264-1274