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Formin-mediated nuclear actin at androgen receptors promotes transcription

Functional mutations identified in patients with androgen insensitivity syndrome, in the formin and actin nucleator DAAM2, uncover signal-regulated nuclear actin assembly at a steroid hormone receptor necessary for transcription.

Julian Knerr
Ralf Werner
Nadine C. Hornig
Research27 Mar 2023
Nature

Volume: 617, P: 616-622
Behavioural responses to a photovoltaic subretinal prosthesis implanted in non-human primates

A near-infrared-light-sensitive photovoltaic subretinal prosthesis triggers behavioural responses in awake macaques, even two years after device implantation.

Paul-Henri Prévot
Kevin Gehere
Serge Picaud
Research02 Dec 2019
Nature Biomedical Engineering

Volume: 4, P: 172-180
Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing

Reiner Siebert and colleagues report whole-genome, whole-exome and transcriptome sequencing of Burkitt lymphomas. They identify recurrent mutations in several genes not previously known to be mutated in Burkitt lymphoma, including ID3, FBXO11, DDX3X and RHOA.

Julia Richter
Matthias Schlesner
Reiner Siebert
Research11 Nov 2012
Nature Genetics

Volume: 44, P: 1316-1320

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