Nature Search

Use of semantic technologies for the development of a dynamic trajectories generator in a Semantic Chemistry eLearning platform

Richard Huber
Kirsten Hantelmann PhD
Adrian Paschke PhD
ResearchOpen Access17 Dec 2010
Nature Precedings

P: 1
A patient with a large recurrent pheochromocytoma demonstrating the pitfalls of diagnosis

This Case Study illustrates some of the potential pitfalls of diagnosis and demonstrates a combination of problems of follow-up biochemical screening in a patient operated for a large pheochromocytoma at increased risk of malignant disease. The difficulty in assessing the presence of disease after initial surgical resection and reaching a diagnosis of malignancy are highlighted.

Jörg Singer
Christian A. Koch
Ralf Paschke
Reviews06 Sept 2011
Nature Reviews Endocrinology

Volume: 7, P: 749-755
Thyroid nodule guidelines: agreement, disagreement and need for future research

In the past decade, several society-sponsored guidelines on thyroid nodules have been published. This Review highlights essential recommendations from these guidelines. Furthermore, the article outlines the few areas of disagreement between the guidelines and discusses areas in which future research is needed.

Ralf Paschke
Laszlo Hegedüs
Hossein Gharib
Reviews01 Mar 2011
Nature Reviews Endocrinology

Volume: 7, P: 354-361
Molecular profiling of thyroid nodule fine-needle aspiration cytology

Fine-needle aspiration cytology is used to diagnose thyroid cancer and determine the risk of malignancy, but some nodules have indeterminate cytology and thus invasive surgery might be required for a definitive diagnosis. This Review discusses the advantages and disadvantages of molecular approaches to diagnosis, which can either rule in or rule out malignancy to optimize surgical planning.

Markus Eszlinger
Lorraine Lau
Ralf Paschke
Reviews31 Mar 2017
Nature Reviews Endocrinology

Volume: 13, P: 415-424
Mechanisms of Disease: hydrogen peroxide, DNA damage and mutagenesis in the development of thyroid tumors

Thyroid nodules are very common; however, their etiology is largely unknown. In this article the authors suggest mechanisms behind the high rates of thyroid tumors. These include the oxidative nature of thyroid hormone synthesis, which is exacerbated by iodine deficiency; this (along with other conditions) can also affect thyroid cell proliferation.

Knut Krohn
Jacqueline Maier
Ralf Paschke
Reviews01 Oct 2007
Nature Clinical Practice Endocrinology & Metabolism

Volume: 3, P: 713-720
Gene expression analysis reveals evidence for inactivation of the TGF-β signaling cascade in autonomously functioning thyroid nodules

Markus Eszlinger
Knut Krohn
Ralf Paschke
Research22 Jan 2004
Oncogene

Volume: 23, P: 795-804
Temperature-sensitive migration dynamics in neutrophil-differentiated HL-60 cells

Galina Khachaturyan
Andrew W. Holle
Ralf Kemkemer
ResearchOpen Access29 Apr 2022
Scientific Reports

Volume: 12, P: 1-13
Linking metabolites in eight bioactive forage species to their in vitro methane reduction potential across several cultivars and harvests

Supriya Verma
Siegfried Wolffram
Carsten Stefan Malisch
ResearchOpen Access21 Jun 2022
Scientific Reports

Volume: 12, P: 1-15

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