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The master male sex determinant Gdf6Y of the turquoise killifish arose through allelic neofunctionalization

How TGF-β family members regulate sex determination in teleost fish is unclear. Here they use turquoise killifish to show that Gdf6Y, in addition to its role in skeletal development, specifies the male sex in somatic supporting cells by autocrine signaling.

Annekatrin Richter
Hanna Mörl
Christoph Englert
ResearchOpen Access09 Jan 2025
Nature Communications

Volume: 16, P: 1-18

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The master male sex determinant Gdf6Y of the turquoise killifish arose through allelic neofunctionalization

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