Nature Search

Hetero-site-specific X-ray pump-probe spectroscopy for femtosecond intramolecular dynamics

Two-color X-ray pulses with controlled time delay allow exciting one site of a molecule and then probing a different site of the same molecule with femtosecond resolution. Here, the authors use this hetero-site pump-probe technique to study charge redistribution and dissociation of the xenon difluoride molecule.

A. Picón
C. S. Lehmann
S. H. Southworth
ResearchOpen Access23 May 2016
Nature Communications

Volume: 7, P: 1-6
Spin-down of the X-ray pulsar GX1 +4 during an extended low state

K. Makishima
T. Ohashi
Y. Tawara
Research23 Jun 1988
Nature

Volume: 333, P: 746-748
Non-linear enhancement of ultrafast X-ray diffraction through transient resonances

Diffraction-before-destruction of ultrashort X-ray pulses can visualize non-equilibrium processes at the nanoscale with sub-femtosecond precision. Here, the authors demonstrate how the brightness and the spatial resolution of such snapshots can be substantially increased despite ionization.

Stephan Kuschel
Phay J. Ho
Tais Gorkhover
ResearchOpen Access20 Jan 2025
Nature Communications

Volume: 16, P: 1-8
Experimental demonstration of attosecond pump–probe spectroscopy with an X-ray free-electron laser

Researchers have demonstrated the generation and control of subfemtosecond pulse pairs from a two-colour X-ray free-electron laser and conducted pump–probe experiments in core-ionized molecules.

Zhaoheng Guo
Taran Driver
Agostino Marinelli
Research11 Apr 2024
Nature Photonics

Volume: 18, P: 691-697
Ultra-efficient ionization of heavy atoms by intense X-ray free-electron laser pulses

Researchers create high ionization states, up to Xe³⁶⁺, using 1.5 keV free-electron laser pulses. The higher than expected ionization may be due to transient resonance-enhanced absorption and the effect may play an important role in interactions of intense X-rays with high-Z elements and radiation damage.

Benedikt Rudek
Sang-Kil Son
Daniel Rolles
Research11 Nov 2012
Nature Photonics

Volume: 6, P: 858-865
Highly reflective white clouds on the western dayside of an exo-Neptune

A complete revolution of exo-Neptune LTT 9779 b was observed with the NIRISS/SOSS instrument onboard the JWST. The resulting full phase curve is indicative of an equatorial jet that transports heat from the dayside to the colder nightside, resulting in an asymmetric distribution of clouds on the planet.

Louis-Philippe Coulombe
Michael Radica
Jake D. Turner
Research25 Feb 2025
Nature Astronomy

Volume: 9, P: 512-525
Detection of tidal dissipation in the solid Earth by satellite tracking and altimetry

R. D. Ray
R. J. Eanes
B. F. Chao
Research13 Jun 1996
Nature

Volume: 381, P: 595-597
A cDNA clone from the Duchenne/Becker muscular dystrophy gene

Arthur H. M. Burghes
Cairine Logan
Peter N. Ray
Research30 Jul 1987
Nature

Volume: 328, P: 434-437
Prophetic Germs

E. RAY LANKESTER
Research01 Nov 1888
Nature

Volume: 39, P: 7
Genetic modifiers of somatic expansion and clinical phenotypes in Huntington’s disease highlight shared and tissue-specific effects

Comparison of genome-wide association studies of HTT CAG repeat expansion in blood to expansion-driven clinical traits in Huntington’s disease identifies shared and distinct modifiers implicating DNA mismatch repair with tissue and cell-type specificity.

Jong-Min Lee
Zachariah L. McLean
Richard H. Myers
Research09 Jun 2025
Nature Genetics

Volume: 57, P: 1426-1436
Does Mercury have a molten core?

PETER E. FRICKER
RAY T. REYNOLDS
PATRICK M. CASSEN
Research29 Jan 1976
Nature

Volume: 259, P: 293-294
Time-resolved synchrotron X-ray micro-tomography datasets of drainage and imbibition in carbonate rocks

Kamaljit Singh
Hannah Menke
Martin J. Blunt
ResearchOpen Access11 Dec 2018
Scientific Data

Volume: 5, P: 1-8
Activation of Raf by ionizing radiation

Usha Kasid
Simeng Suy
Thomas W. Sturgill
Research29 Aug 1996
Nature

Volume: 382, P: 813-816
Spatial microniches of IL-2 combine with IL-10 to drive lung migratory T_H2 cells in response to inhaled allergen

Poholek and colleagues show that, during allergic airway inflammation, the transcription factor Blimp-1 regulates CD4⁺T_H2 cell migration to the lung and define anatomical locations in mediastinal lymph nodes where IL-2 programming induces T_H2 cell polarization.

Kun He
Hanxi Xiao
Amanda C. Poholek
Research11 Oct 2024
Nature Immunology

Volume: 25, P: 2124-2139
Climate variation explains a third of global crop yield variability

Agricultural crops are closely linked to the climate in which they grow, but the extent to which variability in weather influences yield is not well characterized. Here, Ray et al. find that climatic variation explains around a third of the variation in global crop yields, with important regional variations.

Deepak K. Ray
James S. Gerber
Paul C. West
ResearchOpen Access22 Jan 2015
Nature Communications

Volume: 6, P: 1-9
Tollip, a new component of the IL-1RI pathway, links IRAK to the IL-1 receptor

Kimberly Burns
Jonathan Clatworthy
Filippo Volpe
Research10 May 2000
Nature Cell Biology

Volume: 2, P: 346-351
A ring-like accretion structure in M87 connecting its black hole and jet

Spatially resolved images of M87 obtained at a wavelength of 3.5 mm in 2018 show a ring-like accretion structure, the inner (outer) edge of which connects the black hole (jet).

Ru-Sen Lu
Keiichi Asada
Chen-Yu Yu
ResearchOpen Access26 Apr 2023
Nature

Volume: 616, P: 686-690
NFIC regulates ribosomal biology and ER stress in pancreatic acinar cells and restrains PDAC initiation

Pancreatic acinar differentiation can be tumour suppressive for pancreatic ductal adenocarcinoma (PDAC). Here the authors identify nuclear factor I family of transcription factors NFIC as a regulator of pancreatic acinar cell function that restrains mutant KRas-driven pancreas cancer initiation in mice.

Isidoro Cobo
Sumit Paliwal
Francisco X. Real
ResearchOpen Access23 Jun 2023
Nature Communications

Volume: 14, P: 1-16
Event Horizon Telescope observations of the jet launching and collimation in Centaurus A

The millimetre image of the Centaurus A nucleus by the Event Horizon Telescope reveals a highly collimated, asymmetrically edge-brightened jet. The source’s event horizon shadow should be visible at terahertz frequencies, consistent with the universal scale invariance of black holes.

Michael Janssen
Heino Falcke
Shan-Shan Zhao
ResearchOpen Access19 Jul 2021
Nature Astronomy

Volume: 5, P: 1017-1028
Kinase inhibitors modulate huntingtin cell localization and toxicity

Phosphorylation of the Huntington's disease protein Htt by CK2 leads to Htt nuclear translocation in response to stress. Inhibition of other kinase pathways can restore phosphorylation to hypophosphorylated Htt in Huntington's disease and may lead to a therapeutic strategy.

Randy Singh Atwal
Carly R Desmond
Ray Truant
Research29 May 2011
Nature Chemical Biology

Volume: 7, P: 453-460
Time-resolved relaxation and fragmentation of polycyclic aromatic hydrocarbons investigated in the ultrafast XUV-IR regime

Polycyclic aromatic hydrocarbons play an important role in interstellar chemistry, where interaction with high energy photons can induce ionization and fragmentation reactions. Here the authors, with XUV-IR pump-probe experiments, investigate the ultrafast photoinduced dynamics of fluorene, phenanthrene and pyrene, providing insight into their preferred reaction channels.

J. W. L. Lee
D. S. Tikhonov
M. Schnell
ResearchOpen Access20 Oct 2021
Nature Communications

Volume: 12, P: 1-11
A second update on mapping the human genetic architecture of COVID-19

Masahiro Kanai
Shea J. Andrews
Matthew Solomonson
ResearchOpen Access06 Sept 2023
Nature

Volume: 621, P: E7-E26
The role of the transcriptional regulator Ptf1a in converting intestinal to pancreatic progenitors

Yoshiya Kawaguchi
Bonnie Cooper
Christopher V.E. Wright
Research19 Aug 2002
Nature Genetics

Volume: 32, P: 128-134
Scale up manufacturing approach for production of human induced pluripotent stem cell-derived islets using Vertical Wheel® bioreactors

Nidheesh Dadheech
Mario Bermúdez de León
A. M. James Shapiro
ResearchOpen Access29 May 2025
npj Regenerative Medicine

Volume: 10, P: 1-23
Auxetic materials: Avoiding the shrink

Materials that expand laterally when stretched can act as molecular-scale strain amplifiers. This amplification might be exploited in nature and in future technologies.

Ray H. Baughman
Comments & Opinion16 Oct 2003
Nature

Volume: 425, P: 667
Genome sequence, comparative analysis and haplotype structure of the domestic dog

Kerstin Lindblad-Toh
Claire M Wade
Eric S. Lander
Research08 Dec 2005
Nature

Volume: 438, P: 803-819
International genome-wide meta-analysis identifies new primary biliary cirrhosis risk loci and targetable pathogenic pathways

Primary biliary cirrhosis is an autoimmune liver disease with poor therapeutic options. Here Cordell et al. a perform meta-analysis of European genome-wide association studies identifying six novel risk loci and a number of potential therapeutic pathways.

Heather J. Cordell
Younghun Han
Katherine A. Siminovitch
ResearchOpen Access22 Sept 2015
Nature Communications

Volume: 6, P: 1-11
Closing yield gaps through nutrient and water management

Global yields of major crops are analysed using climate, irrigation and new nutrient data to show that large production increases are possible from closing yield gaps to 100% of attainable yields, and that changes in management practices needed to close yield gaps vary considerably by region and current intensity.

Nathaniel D. Mueller
James S. Gerber
Jonathan A. Foley
Research29 Aug 2012
Nature

Volume: 490, P: 254-257
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

The genome of the grey short-tailed opossum Monodelphis domestica has been sequenced and analyzed, giving a first peek at a marsupial's genetic code. Of particular interest are the genetics of the immune system, which has been studied as a model for humans, and of the X chromosome for historical reasons.

Tarjei S. Mikkelsen
Matthew J. Wakefield
Kerstin Lindblad-Toh
Research10 May 2007
Nature

Volume: 447, P: 167-177
What will it take to observe processes in 'real time'?

Even for simple systems, the interpretations of new attosecond measurements are complicated and provide only a glimpse of their potential. Nonetheless, the lasting impact will be the revelation of how short-time dynamics can determine the electronic properties of more complex systems.

Stephen R. Leone
C. William McCurdy
Marc J. J. Vrakking
Comments & Opinion28 Feb 2014
Nature Photonics

Volume: 8, P: 162-166
A nanoscale, multi-parametric flow cytometry-based platform to study mitochondrial heterogeneity and mitochondrial DNA dynamics

Julie MacDonald et al. present a method for mitochondrial isolation using fluorescence-activated mitochondria sorting to facilitate analysis from individual organelles. They validate their platform using a number of downstream assays, including electron microscopy, proteomic profiling, and mtDNA analysis.

Julie A. MacDonald
Alisha M. Bothun
Dori C. Woods
ResearchOpen Access11 Jul 2019
Communications Biology

Volume: 2, P: 1-13
Editorial Expression of Concern: Src kinase as a mediator of convergent molecular abnormalities leading to NMDAR hypoactivity in schizophrenia

A. Banerjee
H.-Y. Wang
C.-G. Hahn
Amendments and Corrections13 May 2025
Molecular Psychiatry

Volume: 30, P: 3359
Preclinical development of a bispecific TNFα/IL-23 neutralising domain antibody as a novel oral treatment for inflammatory bowel disease

Kevin J. Roberts
Marion F. Cubitt
J. Scott Crowe
ResearchOpen Access30 Sept 2021
Scientific Reports

Volume: 11, P: 1-14
Transcriptomic analysis of human sensory neurons in painful diabetic neuropathy reveals inflammation and neuronal loss

Bradford E. Hall
Emma Macdonald
Ashok B. Kulkarni
ResearchOpen Access18 Mar 2022
Scientific Reports

Volume: 12, P: 1-16
Preclinical Development of a Novel, Orally-Administered Anti-Tumour Necrosis Factor Domain Antibody for the Treatment of Inflammatory Bowel Disease

J. Scott Crowe
Kevin J. Roberts
Michael R. West
ResearchOpen Access21 Mar 2018
Scientific Reports

Volume: 8, P: 1-13
Oral Anti-Tumour Necrosis Factor Domain Antibody V565 Provides High Intestinal Concentrations, and Reduces Markers of Inflammation in Ulcerative Colitis Patients

Suhail Nurbhai
Kevin J. Roberts
J. Scott Crowe
ResearchOpen Access01 Oct 2019
Scientific Reports

Volume: 9, P: 1-12
Common variation near CDKN1A, POLD3 and SHROOM2 influences colorectal cancer risk

Richard Houlston and colleagues report a genome-wide association study for colorectal cancer. They report three loci newly associated with colorectal cancer, bringing the total number of common susceptibility loci to 20.

Malcolm G Dunlop
Sara E Dobbins
Richard S Houlston
Research27 May 2012
Nature Genetics

Volume: 44, P: 770-776
The circadian regulator BMAL1 programmes responses to parasitic worm infection via a dendritic cell clock

Thomas W. Hopwood
Sarah Hall
Kathryn J. Else
ResearchOpen Access28 Feb 2018
Scientific Reports

Volume: 8, P: 1-13
A high-resolution copy-number variation resource for clinical and population genetics

Mohammed Uddin
Bhooma Thiruvahindrapuram
Stephen W. Scherer
ResearchOpen Access11 Dec 2014
Genetics in Medicine

Volume: 17, P: 747-752
SLCO5A1 and synaptic assembly genes contribute to impulsivity in juvenile myoclonic epilepsy

Delnaz Roshandel
Eric J. Sanders
Helen Cockerill
ResearchOpen Access28 Sept 2023
npj Genomic Medicine

Volume: 8, P: 1-11
South-South entrepreneurial collaboration in health biotech

A survey of entrepreneurial collaborations among health biotech firms in developing countries reveals a surprisingly high level of collaboration but a lack of emphasis on new or improved health biotech products and processes.

Halla Thorsteinsdóttir
Christina C Melon
Peter A Singer
Special Features01 May 2010
Nature Biotechnology

Volume: 28, P: 407-416
Whole-genome sequencing expands diagnostic utility and improves clinical management in paediatric medicine

Dimitri J Stavropoulos
Daniele Merico
Christian R Marshall
ResearchOpen Access13 Jan 2016
npj Genomic Medicine

Volume: 1, P: 1-9
Patient-reported outcomes during and after definitive chemoradiotherapy for oesophageal cancer

J Rees
C N Hurt
T Crosby
ResearchOpen Access23 Jul 2015
British Journal of Cancer

Volume: 113, P: 603-610
A portable trap with electric lead catches up to 75% of an invasive fish species

Nicholas S. Johnson
Scott Miehls
Tyler Bruning
ResearchOpen Access24 Jun 2016
Scientific Reports

Volume: 6, P: 1-8
Improved diagnostic yield compared with targeted gene sequencing panels suggests a role for whole-genome sequencing as a first-tier genetic test

Anath C Lionel
Gregory Costain
Christian R Marshall
ResearchOpen Access03 Aug 2017
Genetics in Medicine

Volume: 20, P: 435-443
Src kinase as a mediator of convergent molecular abnormalities leading to NMDAR hypoactivity in schizophrenia

A Banerjee
H-Y Wang
C-G Hahn
Research21 Oct 2014
Molecular Psychiatry

Volume: 20, P: 1091-1100

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