Therapeutic decision-making requires integration of complex information on patient-specific and therapy-specific factors. Physicians and prescribers face the daunting task of assessing the efficacy and safety of medications relative to each patient. In this Review, Drs Woosley and Romero discuss the challenges of safe medication prescribing to prevent drug-induced adverse events, and the efforts made to improve clinical decision support systems, using examples from several new evidence-based, online resources.
- Raymond L. Woosley
- Klaus Romero
